V
Vasanthi Sankaranarayanan
Researcher at University of Copenhagen
Publications - 1
Citations - 255
Vasanthi Sankaranarayanan is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Glycopeptide & Antigen. The author has an hindex of 1, co-authored 1 publications receiving 231 citations.
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Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.
Anne Louise Sørensen,Celso A. Reis,Celso A. Reis,Mads Agervig Tarp,Ulla Mandel,Kavitha Ramachandran,Vasanthi Sankaranarayanan,Tilo Schwientek,Ros Graham,Joyce Taylor-Papadimitriou,Michael A. Hollingsworth,Joy Burchell,Henrik Clausen +12 more
TL;DR: Chemoenzymatic synthesis of extended MUC1 TR glycopeptides with cancer-associated O-glycosylation using a panel of recombinant human glycosyltransferases is developed and a MAb with similar specificity as the elicited immune response was generated and shown to have the same remarkable cancer specificity.