V
Veerendra Kumar Madala Halagappa
Researcher at National Institutes of Health
Publications - 2
Citations - 647
Veerendra Kumar Madala Halagappa is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Intermittent fasting & Calorie restriction. The author has an hindex of 2, co-authored 2 publications receiving 571 citations.
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Journal ArticleDOI
Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease.
Veerendra Kumar Madala Halagappa,Zhihong Guo,Michelle Pearson,Yasuji Matsuoka,Roy G. Cutler,Frank M. LaFerla,Mark P. Mattson +6 more
TL;DR: CR and IF dietary regimens can ameliorate age-related deficits in cognitive function by mechanisms that may or may not be related to Abeta and tau pathologies.
Journal ArticleDOI
Prophylactic treatment with paroxetine ameliorates behavioral deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice.
Rhonda L. Nelson,Zhihong Guo,Veerendra Kumar Madala Halagappa,Michelle Pearson,Audrey J. Gray,Yasuji Matsuoka,Martin L. Brown,Bronwen Martin,Titilola Iyun,Stuart Maudsley,Robert Clark,Mark P. Mattson +11 more
TL;DR: It is reported that pre-symptomatic treatment with the antidepressant paroxetine attenuates the disease process and improves cognitive performance in the 3xTgAD mouse model of AD, suggesting a preservation of cognitive function.