V
Venkitasamy Kesavan
Researcher at Indian Institute of Technology Madras
Publications - 86
Citations - 3945
Venkitasamy Kesavan is an academic researcher from Indian Institute of Technology Madras. The author has contributed to research in topics: Enantioselective synthesis & Catalysis. The author has an hindex of 22, co-authored 83 publications receiving 3728 citations. Previous affiliations of Venkitasamy Kesavan include Centre national de la recherche scientifique & Alnylam Pharmaceuticals.
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Katalytische aerobe Oxidation von Cycloalkanen mit nanostrukturierten amorphen Metallen und Legierungen
Venkitasamy Kesavan,Pennadam S. Sivanand,Srinivasan Chandrasekaran,Yuri Koltypin,Aharon Gedanken +4 more
TL;DR: In this paper, the authors present an aerobeoxidation von Cycloalkanen zu Cyclohexanol with nanostrukturierten amorphen Metallen wie Fe und Co and der amorphens Legierung Fe20Ni80 als Katalysator erzielt werden.
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Highly stable triple helix formation by homopyrimidine (L)-acyclic threoninol nucleic acids with single stranded DNA and RNA
TL;DR: It was demonstrated that (L)-aTNA triplexes are able to stop primer extension on a DNA template, showing the potential of (L), aTNA for antisense applications.
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Polysorbate Surfactants as Drug Carriers: Tween 20-Amphotericin B Conjugates as Anti-Fungal and Anti-Leishmanial Agents
Vasanthan Ravichandran,Venkitasamy Kesavan,Sandrine Cojean,Philippe M. Loiseau,Athipettah Jayakrishnan +4 more
TL;DR: Synthesis of drug conjugates with surfactants such as Tween-20 could open up new opportunities to improve the solubility of many drugs, reduce their toxicity and could possibly target the brain as polysorbates known to facilitate nanoparticulate systems to cross the blood-brain barrier.
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Acyclic butyl nucleic acid (BuNA): a novel scaffold for A-switch
Vipin Kumar,Venkitasamy Kesavan +1 more
TL;DR: This is the first report of the construction of an A-switch using artificial nucleic acids and thermal melting studies suggest that at neutral pH, poly BuNA(A) is a weakly organized single strand, while at low pH it adopts a highly organized and rigid structure.
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Catalytic enantioselective Michael addition of 2-substituted benzofuran-3-ones to 2-enoyl pyridines
TL;DR: An organocatalytic diastereo- and enantioselective synthesis of 2,2'-disubstituted benzofuran-3-ones bearing adjacent quaternary and tertiary stereocenters has been achieved through Michael addition of 2-substituting benzofuras to 2-enoyl pyridines.