V
Vera Samoilova
Researcher at University of Münster
Publications - 35
Citations - 915
Vera Samoilova is an academic researcher from University of Münster. The author has contributed to research in topics: Endothelium & Nitric oxide synthase. The author has an hindex of 16, co-authored 31 publications receiving 759 citations.
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Journal ArticleDOI
Non-specific binding of antibodies in immunohistochemistry: fallacies and facts.
TL;DR: It is determined that traditionally used protein blocking steps are unnecessary in the immunostaining of routinely fixed cell and tissue samples.
Journal ArticleDOI
Vascular smooth muscle and nitric oxide synthase
Igor B. Buchwalow,Thomas Podzuweit,Werner Böcker,Vera Samoilova,Sylvia Thomas,Maren Wellner,Hideo A. Baba,Horst Robenek,Jürgen Schnekenburger,Markus M. Lerch +9 more
TL;DR: A novel supersensitive immunocytochemical technique of signal amplification with tyramide and electron microscopic immunogold labeling complemented with Western blotting provides the first evidence that, in contrast to the currently accepted view, VSMC in various blood vessels express all three NOS isoforms depending on the blood vessel type.
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Tryptase as a polyfunctional component of mast cells.
TL;DR: The current knowledge about mast cell tryptase as one of the mast cell secretome proteases is discussed, with microscopic images of mast celltryptases visualized using immunohistochemical staining.
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Protein tyrosine phosphatase kappa and SHP-1 are involved in the regulation of cell-cell contacts at adherens junctions in the exocrine pancreas.
J. Schnekenburger,Julia Mayerle,Burkhard Krüger,Igor B. Buchwalow,Frank-Ulrich Weiss,Elke Albrecht,Vera Samoilova,Wolfram Domschke,Markus M. Lerch +8 more
TL;DR: It is suggested that a definitive role for the protein tyrosine phosphatases PTPκ and SHP-1 in the regulation, maintenance, and restitution of cell adhesions in a complex epithelial organ such as the pancreas is suggested.
Journal ArticleDOI
An in situ evidence for autocrine function of NO in the vasculature.
Igor B. Buchwalow,Thomas Podzuweit,Vera Samoilova,Maren Wellner,Hermann Haller,Stephanie Grote,Susanne Aleth,Werner Boecker,Wilhelm Schmitz,Joachim Neumann +9 more
TL;DR: These findings challenge the commonly accepted view that the expression of NO synthase is restricted to vascular endothelial cells and lends further support to an alternative mechanism, by which constitutive local NOS expression in VSMC may modulate vascular functions in an endothelium-independent manner.