W
Werner Boecker
Researcher at University of Münster
Publications - 105
Citations - 6129
Werner Boecker is an academic researcher from University of Münster. The author has contributed to research in topics: Breast cancer & Myoepithelial cell. The author has an hindex of 42, co-authored 103 publications receiving 5868 citations. Previous affiliations of Werner Boecker include University of Bonn.
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Journal ArticleDOI
Comparative genomic hybridization of ductal carcinoma in situ of the breast-evidence of multiple genetic pathways.
Horst Buerger,Friedrich Otterbach,Ronald Simon,Christopher Poremba,Raihanatou Diallo,Thomas Decker,Lutz Riethdorf,C. Brinkschmidt,Barbara Dockhorn-Dworniczak,Werner Boecker +9 more
TL;DR: Analysis of paraffin‐embedded specimens of DCIS and six associated invasive carcinomas revealed a genetic pattern almost identical to the one seen in the DCIS counterpart, characterize DCIS as a genetically far‐advanced, heterogeneous lesion and as a direct precursor of invasive breast cancer.
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Different genetic pathways in the evolution of invasive breast cancer are associated with distinct morphological subtypes.
Horst Buerger,Friedrich Otterbach,Ronald Simon,K L Schäfer,Christopher Poremba,Raihanatou Diallo,C. Brinkschmidt,Barbara Dockhorn-Dworniczak,Werner Boecker +8 more
TL;DR: Data demonstrate the close genetic similarity of well‐, intermediately, and poorly differentiated DCIS and distinct morphological types of invasive breast carcinoma, providing further evidence that DCIS is a direct precursor lesion ofvasive breast cancer and that various evolutionary genetic pathways exist.
Journal ArticleDOI
Cytogenetic alterations and cytokeratin expression patterns in breast cancer: integrating a new model of breast differentiation into cytogenetic pathways of breast carcinogenesis.
Eberhard Korsching,J Packeisen,Konstantin Agelopoulos,Martin Eisenacher,Reinhard Voss,Jorma Isola,Paul J. van Diest,Burkhard Brandt,Werner Boecker,Horst Buerger +9 more
TL;DR: The data give the first hints to the hypothesis that different cellular subgroups in the female breast give rise to subgroups of breast carcinomas with differing protein expression and cytogenetic alteration patterns that may be related to clinical behavior.
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The origin of vimentin expression in invasive breast cancer: epithelial-mesenchymal transition, myoepithelial histogenesis or histogenesis from progenitor cells with bilinear differentiation potential?
Eberhard Korsching,J Packeisen,Cornelia Liedtke,D. Hungermann,Pia Wülfing,Paul J. van Diest,Burkhard Brandt,Werner Boecker,Horst Buerger +8 more
TL;DR: The alternative hypothesis that vimentin‐expressing breast carcinomas may derive from breast progenitor cells with bilinear (glandular and myoepithelial) differentiation potential is proposed.
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Pathological work-up of sentinel lymph nodes in breast cancer. Review of current data to be considered for the formulation of guidelines
Gábor Cserni,Isabel Amendoeira,N Apostolikas,Jean-Pierre Bellocq,Simonetta Bianchi,Giovanni Bussolati,Werner Boecker,Bettina Borisch,C E Connolly,Thomas Decker,Peter A. Dervan,Maria Drijkoningen,Ian O. Ellis,C. W. Elston,Vincenzo Eusebi,D Faverly,Päivi Heikkilä,Roland Holland,H. Kerner,Janina Kulka,Jocelyne Jacquemier,Manuela Lacerda,J. Martinez-Penuela,C. de Miguel,Johannes L. Peterse,Fritz Rank,Peter Regitnig,Angelika Reiner,Anna Sapino,Brigitte Sigal-Zafrani,A.M. Tanous,S. Thorstenson,E. Zozaya,Clive A. Wells +33 more
TL;DR: An evaluation of the accuracy of SN biopsy as a staging procedure, the yields of different sectioning methods and the immunohistochemical detection of metastatic cells are reviewed and it is suggested that approximately 18% of the cases may be associated with further nodal (non-SN) metastases.