V
Veronika Martinková
Publications - 2
Citations - 32
Veronika Martinková is an academic researcher. The author has contributed to research in topics: Protein–protein interaction & Cancer. The author has an hindex of 1, co-authored 2 publications receiving 21 citations.
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Human Stress-inducible Hsp70 Has a High Propensity to Form ATP-dependent Antiparallel Dimers That Are Differentially Regulated by Cochaperone Binding.
Filip Trčka,Michal Durech,Pavla Vankova,Pavla Vankova,Josef Chmelík,Josef Chmelík,Veronika Martinková,Jiri Hausner,Jiri Hausner,Alan Kadek,Alan Kadek,Julien Marcoux,Tomáš Klumpler,Borivoj Vojtesek,Petr Müller,Petr Man,Petr Man +16 more
TL;DR: Structural evidence of robust ATP-dependent antiparallel dimerization of human inducible Hsp70 protein is provided and a novel role of TPR domain cochaperones in multichaperone complexes involving HSp70 ATP-bound dimers is suggested.
Journal ArticleDOI
The Role of HSP70 in Cancer and its Exploitation as a Therapeutic Target.
TL;DR: Information is summarized on the structure of HSP70 and its role in maintaining protein homeostasis in normal and cancer cells and the mechanisms of H SP70 inhibition by low-molecular weight compounds and their application in targeted antitumor therapy are described.