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Vianney Tricou

Researcher at Takeda Pharmaceutical Company

Publications -  38
Citations -  1545

Vianney Tricou is an academic researcher from Takeda Pharmaceutical Company. The author has contributed to research in topics: Dengue vaccine & Dengue fever. The author has an hindex of 12, co-authored 30 publications receiving 1224 citations. Previous affiliations of Vianney Tricou include University of Oxford & Pasteur Institute.

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A randomized controlled trial of chloroquine for the treatment of dengue in Vietnamese adults.

TL;DR: CQ does not reduce the durations of viraemia and NS1 antigenaemia in dengue patients and was associated with significantly more adverse events, primarily vomiting.
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Diagnostic accuracy of NS1 ELISA and lateral flow rapid tests for dengue sensitivity, specificity and relationship to viraemia and antibody responses.

TL;DR: Data suggest NS1 assays deserve inclusion in the diagnostic evaluation of dengue patients, but with due consideration for the limitations in patients who present late in their illness or have a concomitant humoral immune response.
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Kinetics of Viremia and NS1 Antigenemia Are Shaped by Immune Status and Virus Serotype in Adults with Dengue

TL;DR: The findings suggest that the early magnitude of viremia is positively associated with disease severity, and the clearance of DENV is associated with immune status, and there are serotype dependent differences in infection kinetics.
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Comparison of two dengue NS1 rapid tests for sensitivity, specificity and relationship to viraemia and antibody responses

TL;DR: The data suggest that the NS1 test component of these assays are highly specific and have similar levels of sensitivity, and the IgM parameter in the SD Duo test improved overall test sensitivity without compromising specificity.
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Efficacy of a tetravalent dengue vaccine in healthy children aged 4-16 years: a randomised, placebo-controlled, phase 3 trial.

TL;DR: TAK-003 was well tolerated and efficacious against symptomatic dengue in children regardless of serostatus before immunisation, warranting continued follow-up to assess longer-term vaccine performance.