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Vicky E MacRae

Researcher at University of Edinburgh

Publications -  91
Citations -  3164

Vicky E MacRae is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Calcification & Vascular smooth muscle. The author has an hindex of 30, co-authored 83 publications receiving 2566 citations. Previous affiliations of Vicky E MacRae include Royal Hospital for Sick Children & The Roslin Institute.

Papers
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Journal ArticleDOI

Extragonadal Effects of Follicle-Stimulating Hormone on Osteoporosis and Cardiovascular Disease in Women during Menopausal Transition.

Dongxing Zhu, +4 more
- 01 Aug 2018 - 
TL;DR: This work reviews the key actions through which FSH contributes to the risk of osteoporosis and cardiovascular disease in women as they transition through menopause and suggests new opportunities for improving health-span for postmenopausal women.
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Cartilage development and degeneration: a Wnt Wnt situation

Katherine Staines, +2 more
- 01 Dec 2012 - 
TL;DR: The role of the Wnt signaling pathway in cartilage degeneration and its potential to act as a target for therapy in osteoarthritis is detailed.
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Increased bone mass, altered trabecular architecture and modified growth plate organization in the growing skeleton of SOCS2 deficient mice.

Vicky E MacRae, +7 more
- 01 Feb 2009 - 
TL;DR: The data indicate that physiological levels of SOCS2 negatively regulate bone formation and endochondral growth and suggest that pro‐inflammatory cytokines mediate their inhibitory effects on longitudinal bone growth through a mechanism that is independent of SOCs2.
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Optimisation of the differing conditions required for bone formation in vitro by primary osteoblasts from mice and rats.

Isabel R. Orriss, +4 more
- 01 Nov 2014 - 
TL;DR: The present study established a reliable technique for inducing mouse osteoblasts to form bone in vitro and a more effective method for culturing bone-forming rat osteobasts and identified key differences in optimal culture conditions between mouse and rat osteoblast.
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ENPP1 in the Regulation of Mineralization and Beyond.

Fiona Roberts, +3 more
- 21 Feb 2019 - 
TL;DR: A fuller understanding of the pathways through which ENPP1 acts may help to develop novel therapeutic strategies for commonly diagnosed morbidities, including diabetes, cancer, cardiovascular disease, and osteoarthritis.