V
Victoria Gonzalo
Researcher at University of Barcelona
Publications - 32
Citations - 821
Victoria Gonzalo is an academic researcher from University of Barcelona. The author has contributed to research in topics: Colorectal cancer & Lynch syndrome. The author has an hindex of 15, co-authored 30 publications receiving 742 citations.
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Journal ArticleDOI
Identification of MYH Mutation Carriers in Colorectal Cancer: A Multicenter, Case-Control, Population-Based Study
Francesc Balaguer,Sergi Castellví–Bel,Antoni Castells,Montserrat Andreu,Jenifer Muñoz,Javier P. Gisbert,Xavier Llor,Rodrigo Jover,Rafael de Cid,Victoria Gonzalo,Xavier Bessa,Rosa M. Xicola,Elisenda Pons,Cristina Alenda,Artemio Payá,Josep M. Piqué +15 more
TL;DR: This study proposes the first set of clinical criteria designed to identify CRC patients with biallelic MYH mutations, and it argues against an increased risk for monoallelic carriers.
Journal ArticleDOI
Colorectal cancer risk factors in patients with serrated polyposis syndrome: a large multicentre study
Sabela Carballal,Daniel Rodríguez-Alcalde,Leticia Moreira,Luis Hernández,Lorena Rodríguez,Francisco Rodríguez-Moranta,Victoria Gonzalo,Luis Bujanda,Xavier Bessa,Carmen Poves,Joaquín Cubiella,Inés Castro,Mariano González,Eloisa Moya,Susana Oquiñena,Joan Clofent,Enrique Quintero,Pilar Esteban,Virginia Piñol,F. Fernandez,Rodrigo Jover,Lucía Cid,María López-Cerón,Miriam Cuatrecasas,Jorge López-Vicente,Maria Liz Leoz,Liseth Rivero-Sánchez,Antoni Castells,Maria Pellise,Francesc Balaguer +29 more
TL;DR: Specific polyp features (SSA/P histology, proximal location and presence of high-grade dysplasia) should be used to guide clinical management and patients with SPS have an increased risk of CRC, although lower than previously published.
Journal ArticleDOI
MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer
María Dolores Giráldez,Francesc Balaguer,Luis Bujanda,Miriam Cuatrecasas,Jenifer Muñoz,Virginia Alonso-Espinaco,Mikel Larzabal,Anna Petit,Victoria Gonzalo,Teresa Ocaña,Leticia Moreira,José María Enríquez-Navascués,C. Richard Boland,Ajay Goel,Antoni Castells,Sergi Castellví-Bel +15 more
TL;DR: Loss of MSH6 expression is the predominant cause of MMR deficiency in early-onset CRC and should be included in the genetic counseling of patients and their relatives, according to the findings.
Journal ArticleDOI
Aberrant gene promoter methylation associated with sporadic multiple colorectal cancer
Victoria Gonzalo,Juan José Lozano,Jenifer Muñoz,Francesc Balaguer,Maria Pellise,Cristina Rodríguez de Miguel,Montserrat Andreu,Rodrigo Jover,Xavier Llor,M. Dolores Giráldez,Teresa Ocaña,Anna Serradesanferm,Virginia Alonso-Espinaco,Mireya Jimeno,Miriam Cuatrecasas,Oriol Sendino,Sergi Castellví-Bel,Antoni Castells +17 more
TL;DR: A proof-of-concept that gene promoter methylation is associated with tumor multiplicity is provided, which may have noteworthy implications in the prevention of patients with sporadic CRC.
Journal ArticleDOI
Susceptibility Genetic Variants Associated With Colorectal Cancer Risk Correlate With Cancer Phenotype
Anna Abulí,Xavier Bessa,Juan R. González,Clara Ruiz–Ponte,Alejandro Cáceres,Jenifer Muñoz,Victoria Gonzalo,Francesc Balaguer,Ceres Fernández–Rozadilla,Dolors Gonzalez,Luísa Castro,Juan Clofent,Luis Bujanda,Joaquín Cubiella,Josep Ma Reñé,Juan Diego Morillas,Angel Lanas,Joaquim Rigau,Ana Ma García,Mercedes Latorre,Joan Saló,Fernando Fernández Bañares,Lidia Argüello,Elena Peña,Angels Vilella,Sabino Riestra,Ramiro Carreño,Artemio Payá,Cristina Alenda,Rosa M. Xicola,Brian J. Doyle,Rodrigo Jover,Xavier Llor,Angel Carracedo,Antoni Castells,Sergi Castellví–Bel,Montserrat Andreu +36 more
TL;DR: CRC susceptibility variants at 8q23.3, 8q24.21, and 16q22.2 appear to be associated with cancer phenotype, and these findings might be used to develop screening and surveillance strategies.