V
Viktor Wixler
Researcher at University of Münster
Publications - 48
Citations - 1987
Viktor Wixler is an academic researcher from University of Münster. The author has contributed to research in topics: Virus & Influenza A virus. The author has an hindex of 23, co-authored 48 publications receiving 1713 citations. Previous affiliations of Viktor Wixler include University of Erlangen-Nuremberg & University of Cologne.
Papers
More filters
Journal ArticleDOI
Polyethylenimine, a cost-effective transfection reagent
Christina Ehrhardt,Mirco Schmolke,Andreas Matzke,Alexander Knoblauch,Carola Will,Viktor Wixler,Stephan Ludwig +6 more
TL;DR: The non-modified PEI reagent was used to optimize transfection protocols for different cell-lines and was able to transiently transfect a number of cell- lines up to 40–90%.
Journal ArticleDOI
Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation
Thomas Vogl,Athanasios Stratis,Viktor Wixler,Tom Völler,Sumita Thurainayagam,Selina K. Jorch,Stefanie Zenker,Alena Dreiling,Deblina Chakraborty,Mareike Fröhling,Peter Paruzel,Corinna Wehmeyer,Sven Hermann,Olympia Papantonopoulou,Christiane Geyer,Karin Loser,Michael Schäfers,Stephan Ludwig,Monika Stoll,Tomas Leanderson,Joachim L. Schultze,Simone König,Thomas Pap,Johannes Roth +23 more
TL;DR: This work unravels for the first time, to the knowledge, a mechanism of autoinhibition in mice and humans restricting S100-DAMP activity to local sites of inflammation, and identifies specific peptide sequences within the second calcium-binding EF-hands triggering TLR4/MD2-dependent inflammation.
Journal ArticleDOI
The LIM-only protein FHL2 interacts with β-catenin and promotes differentiation of mouse myoblasts
Bernd Martin,Richard Schneider,Stefanie Janetzky,Zoe Waibler,Petra Pandur,Michael Kühl,Jürgen Behrens,Klaus von der Mark,Anna Starzinski-Powitz,Viktor Wixler +9 more
TL;DR: FHL2 is a muscle-specific repressor of LEF/TCF target genes and promotes myogenic differentiation by interacting with β-catenin, suggesting an important role of FHL2 in muscle development.
Journal ArticleDOI
The LIM-only Protein DRAL/FHL2 Binds to the Cytoplasmic Domain of Several α and β Integrin Chains and Is Recruited to Adhesion Complexes
Viktor Wixler,Dirk Geerts,Emmanuel Laplantine,Daniel Westhoff,Neil Smyth,Monique Aumailley,Arnoud Sonnenberg,Mats Paulsson +7 more
TL;DR: The results, together with the fact that full-length DRAL/FHL2 is found in cell adhesion complexes, suggest that it is an adaptor/docking protein involved in integrin signaling pathways.
Journal ArticleDOI
The LIM-only Proteins FHL2 and FHL3 Interact with α- and β-Subunits of the Muscle α7β1 Integrin Receptor
Thomas Samson,Neil Smyth,Stefanie Janetzky,Olaf Wendler,Judith M. Müller,Roland Schüle,Helga von der Mark,Klaus von der Mark,Viktor Wixler +8 more
TL;DR: It is shown that FHL2 and FHL3 are novel α7β1 integrin-interacting proteins that bind both the α- and the β-subunit as well as different splice isoforms, and that the suprastructure of the whole molecule is important for these associations rather than any single LIM domain.