V
Vincent E. Ziegler
Researcher at Washington University in St. Louis
Publications - 16
Citations - 8591
Vincent E. Ziegler is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Nortriptyline & Amitriptyline. The author has an hindex of 12, co-authored 16 publications receiving 7786 citations.
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A rating scale for mania: reliability, validity and sensitivity.
TL;DR: The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently, and also correlated with the number of days of subsequent stay in hospital.
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Validity of the Zung Self-rating Depression Scale.
TL;DR: The Zung Self-Rating Depression Scale (ZSDS) correlated well with the treating physician's global rating in 26 depressed out-patients during the six weeks of treatment with a tricyclic antidepressant.
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Nortriptyline plasma levels and therapeutic response.
TL;DR: Nine depressed outpatients were treated for 6 wk with amitriptyline and the percentage of recovered patients increases significantly as the plasma levels rise to 250 ng/ml, the maximum plasma level considered in this study.
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Tricyclic Antidepressant Overdose: Incidence of Symptoms
TL;DR: Plasma TCA measurements more reliably define patients who are at risk for major medical complications following overdose than does the amount of drug ingested by history.
Journal ArticleDOI
Tricyclic antidepressant plasma levels and adverse effects after overdose.
James M. Petit,Duane G. Spiker,Joseph F. Ruwitch,Vincent E. Ziegler,Alan N. Weiss,John T. Biggs +5 more
TL;DR: Measurement of total TAD (free and protein‐bound) appears to correlate well with biologic response as well as with major adverse effects and electrocardiographic findings.