V
Vincent G. Bain
Researcher at University of Alberta
Publications - 123
Citations - 8987
Vincent G. Bain is an academic researcher from University of Alberta. The author has contributed to research in topics: Liver transplantation & Hepatitis C. The author has an hindex of 41, co-authored 121 publications receiving 8482 citations. Previous affiliations of Vincent G. Bain include University of British Columbia & University of Alberta Hospital.
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Journal ArticleDOI
Randomised trial of interferon alpha2b plus ribavirin for 48 weeks or for 24 weeks versus interferon alpha2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (IHIT)
Thierry Poynard,Patrick Marcellin,Samuel S. Lee,Christian Niederau,Gerald S. Minuk,Gaetano Ideo,Vincent G. Bain,Jenny Heathcote,Stefan Zeuzem,Christian Trepo,Janice K. Albrecht +10 more
TL;DR: AnInterferon α2b plus ribavirin combination is more effective than 48 weeks of interferonα2b monotherapy and has an acceptable safety profile and patients with few favourable factors benefit more from extending the duration of combination therapy to 48 weeks.
Journal ArticleDOI
Muscle Wasting Is Associated With Mortality in Patients With Cirrhosis
Aldo Montaño Loza,Judith Meza Junco,Carla M. Prado,Jessica R. Lieffers,Vickie E. Baracos,Vincent G. Bain,Michael B. Sawyer +6 more
TL;DR: Sarcopenia is associated with mortality in patients with cirrhosis and does not correlate with the degree of liver dysfunction evaluated by using conventional scoring systems, but scoring systems should include evaluation of sarcopenia to better assess mortality among patients with Cirrhosis.
ORIGINAL ARTICLES—LIVER, PANCREAS, AND BILIARY TRACT Muscle Wasting Is Associated With Mortality in Patients With Cirrhosis
Aldo J. Montano-Loza,Carla M. Prado,Jessica R. Lieffers,Vickie E. Baracos,Vincent G. Bain,Michael B. Sawyer +5 more
TL;DR: Sarcopenia, defined as a low level of muscle mass, occurs in patients with cirrhosis and is associated with mortality and prognosis in patients undergoing liver transplantation.
Journal ArticleDOI
Mutation in HBV RNA-dependent DNA polymerase confers resistance to lamivudine in vivo.
Graham Tipples,Mang Ma,Karl P. Fischer,Vincent G. Bain,Norman M. Kneteman,David L.J. Tyrrell +5 more
TL;DR: It is likely that the methionine‐to‐ isoleucine mutation in the YMDD motif of the HBV polymerase contributes significantly to the lamivudine‐resistance of HBV isolated from this patient.
Journal ArticleDOI
Severe muscle depletion in patients on the liver transplant wait list: Its prevalence and independent prognostic value
Puneeta Tandon,Michael Ney,Ivana Irwin,Mang Ma,Leah Gramlich,Vincent G. Bain,Nina Esfandiari,Vickie E. Baracos,Aldo J. Montano-Loza,Robert P. Myers,Robert P. Myers +10 more
TL;DR: Sarcopenia is associated with increased waiting‐list mortality and is poorly predicted by subjective nutritional assessment tools such as BMI and subjective global assessment.