Vincent H.L. Lee

TL;DR: "Fundamentals Changing Needs in Drug Delivery in the Era of Peptide and Protein Drugs: Case History of an LHRH Analog Mucosal Dosage Forms for Peptides and Protein Delivery Controlled Delivery Systems for Peptonides Characterization of the Toxicity Profile of Peptonide andprotein Therapeutics Reduction of Immunogenicity and Extension of Circulating Half-Life of PePTides and Proteins Regulatory Perspective of Peptic Drug Development.

TL;DR: Possible new criteria and class boundaries are proposed for additional biowaivers based on the underlying physiology of the gastrointestinal tract based on conservative criteria and potential biowaiver extension.

TL;DR: The focus of this review is on recent developments in topical ocular drug delivery systems relative to their success in overcoming the constraints imposed by the eye and to the improvements that have yet to be made.

TL;DR: The nature and magnitude of the penetration and enzymatic barriers to peptide and protein drug absorption are described and the effectiveness and limitations of the approaches that have been used to overcome such barriers are reviewed.