V
Vincent Soubannier
Researcher at Montreal Neurological Institute and Hospital
Publications - 27
Citations - 3380
Vincent Soubannier is an academic researcher from Montreal Neurological Institute and Hospital. The author has contributed to research in topics: ATP synthase & ATP synthase gamma subunit. The author has an hindex of 14, co-authored 25 publications receiving 2849 citations. Previous affiliations of Vincent Soubannier include Center for Integrated Protein Science Munich & Rosalind Franklin University of Medicine and Science.
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Journal ArticleDOI
The ATP synthase is involved in generating mitochondrial cristae morphology
Patrick Paumard,Jacques Vaillier,Bénédicte Coulary,Jacques Schaeffer,Vincent Soubannier,David M. Mueller,Daniel Brèthes,Jean-Paul di Rago,Jean Velours +8 more
TL;DR: A model is proposed of the assembly of ATP synthase dimers, taking into account the oligomerization of the yeast enzyme and earlier data on the ultrastructure of mitochondrial cristae, which suggests that the association of mitochondria of yeast cells deficient in either subunits e or g is involved in the control of the biogenesis of the inner mitochondrial membrane.
Journal ArticleDOI
Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control.
TL;DR: It is hypothesize that loss of this parkin‐ and PINK1‐dependent trafficking mechanism impairs the ability of mitochondria to selectively degrade oxidized and damaged proteins leading, over time, to the mitochondrial dysfunction noted in PD.
Journal ArticleDOI
A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes
Vincent Soubannier,Gian-Luca McLelland,Rodolfo Zunino,Emelie Braschi,Peter Rippstein,Edward A. Fon,Heidi M. McBride +6 more
TL;DR: A novel vesicle transport route between the mitochondria and lysosomes is characterized, providing insights into the basic mechanisms of mitochondrial quality control and suggesting that vesicles delivery complements mitophagy.
Journal ArticleDOI
OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand.
David A. Patten,Jacob Wong,Mireille Khacho,Vincent Soubannier,Ryan J. Mailloux,Karine Pilon-Larose,Jason G. MacLaurin,David S. Park,Heidi M. McBride,Laura Trinkle-Mulcahy,Mary-Ellen Harper,Marc Germain,Ruth S. Slack +12 more
TL;DR: A novel way in which OPA1 senses energy substrate availability is proposed, which modulates its function in the regulation of mitochondrial architecture in a SLC25A protein‐dependent manner.
Journal ArticleDOI
Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e/g.
Regina Rabl,Vincent Soubannier,Vincent Soubannier,Roland Scholz,Frank Vogel,Nadine Mendl,Andreja Vasiljev-Neumeyer,Christian Körner,Ravi Jagasia,Thomas A. Keil,Wolfgang Baumeister,Marek Cyrklaff,Walter Neupert,Andreas S. Reichert,Andreas S. Reichert +14 more
TL;DR: A model in which the antagonism between Fcj1 and Su e/g locally modulates the F1FO oligomeric state, thereby controlling membrane curvature of cristae to generate CJs and cristAE tips is proposed.