V
Vincent Théry
Researcher at University of Auvergne
Publications - 42
Citations - 1191
Vincent Théry is an academic researcher from University of Auvergne. The author has contributed to research in topics: Catalysis & Kinase. The author has an hindex of 16, co-authored 41 publications receiving 1081 citations. Previous affiliations of Vincent Théry include Blaise Pascal University & Centre national de la recherche scientifique.
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Quantum mechanical computations on very large molecular systems: the local self-consistent field method
TL;DR: Simulations of large systems, involving local changes of electronic structure, are possible at a good degree of approximation by introducing a quantum chemical part in molecular dynamics studies.
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Click Chelators for Platinum‐Based Anticancer Drugs
Aurélie Maisonial,Patrycja Serafin,Mounir Traïkia,Eric Debiton,Vincent Théry,David J. Aitken,Pascale Lemoine,Bernard Viossat,Arnaud Gautier +8 more
TL;DR: In this article, the triazole-amine triazoles from click chemistry are convenient ligands for the formation of platinum complexes bearing combined triazola-amine or triazolara-carboxylate moieties and striking differences in the chelation modes are observed between the two series.
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Synthesis, protein kinase inhibitory potencies, and in vitro antiproliferative activities of meridianin derivatives.
Francis Giraud,Georges Alves,Georges Alves,Eric Debiton,Lionel Nauton,Lionel Nauton,Vincent Théry,Vincent Théry,Emilie Durieu,Yoan Ferandin,Olivier Lozach,Laurent Meijer,Fabrice Anizon,Fabrice Anizon,Elisabeth Pereira,Elisabeth Pereira,Pascale Moreau,Pascale Moreau +17 more
TL;DR: In this paper, the synthesis of new meridianin derivatives is described and the most effective compounds toward these two kinase families are the 6-and 7-bromo derivatives 30, 33, and 34 that showed more than 45fold selectivity toward DYRK1A/CLK1 kinases over the other kinases tested.
Synthesis, protein kinase inhibitory potencies and in vitro antiproliferative activities of meridianin derivatives
Pascale Moreau,Francis Giraud,Elisabeth Pereira,Fabrice Anizon,Georges Alves,Eric Debiton,Lionel Nauton,Vincent Théry,Olivier Lozach,Laurent Meijer +9 more
TL;DR: The 6- and 7-bromo derivatives 30, 33, and 34 that showed more than 45-fold selectivity toward DYRK1A/CLK1 kinases over the other kinases tested could thus be developed toward potent and selective inhibitors of key RNA splicing regulators and potential therapeutic agents.
Journal ArticleDOI
12-Helix folding of cyclobutane beta-amino acid oligomers.
Carlos Fernandes,Sophie Faure,Elisabeth Pereira,Vincent Théry,Valérie Declerck,Régis Guillot,David J. Aitken +6 more
TL;DR: Observations suggest a marked preference for the folding of trans-2-aminocyclobutane carboxylic acid oligomers into a well-defined 12-helical conformation in both solution and the solid state.