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Vincenzo Zimmitti

Researcher at University of L'Aquila

Publications -  5
Citations -  303

Vincenzo Zimmitti is an academic researcher from University of L'Aquila. The author has contributed to research in topics: Neurotrophic factors & Glutathione. The author has an hindex of 4, co-authored 5 publications receiving 281 citations.

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Fifty hertz extremely low-frequency magnetic field exposure elicits redox and trophic response in rat-cortical neurons

TL;DR: Investigating the effects of exposures to two different 50 Hz sinusoidal ELF‐MFs intensities in maturing rat cortical neurons' major anti‐oxidative enzymatic and non‐enzymatic cellular protection systems and linear regression analysis suggested a positive correlation between reduced glutathione (GSH) and ROS levels in 1 mT MF‐exposed cells.
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Methylglyoxal causes strong weakening of detoxifying capacity and apoptotic cell death in rat hippocampal neurons

TL;DR: The findings suggest that methylglyoxal-induced neurotoxicity occurs through the impairment of detoxification pathway and depletion of reduced glutathione, which triggers widespread apoptotic cell death, occurring through the convergence of both mitochondrial and Fas-receptor pathways.
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Chronic exposure to 50 Hz magnetic fields causes a significant weakening of antioxidant defence systems in aged rat brain

TL;DR: The data seem to suggest that the exposure to ELF-MFs may act as a risk factor for the occurrence of oxidative stress-based nervous system pathologies associated with ageing.
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Transient maintenance in bioreactor improves health of neuronal cells.

TL;DR: Evidence is provided that primary neuronal cells, at an early stage of development, can be maintained in a suspension condition before adherent plating, leading cells to development and maturation in a tridimensional state.
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Bioreactor Transient Exposure Activates Specific Neurotrophic Pathway in Cortical Neurons

TL;DR: It is postulate that relatively short microgravitational stimuli, applied to neural cells during the developmental stage, exert a long time activation of specific neurotrophic pathways.