F
Fernanda Amicarelli
Researcher at University of L'Aquila
Publications - 110
Citations - 3846
Fernanda Amicarelli is an academic researcher from University of L'Aquila. The author has contributed to research in topics: Oxidative stress & Superoxide dismutase. The author has an hindex of 31, co-authored 107 publications receiving 3258 citations. Previous affiliations of Fernanda Amicarelli include National Research Council & University of Chieti-Pescara.
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Journal ArticleDOI
Cellular and molecular aspects of ovarian follicle ageing
Carla Tatone,Fernanda Amicarelli,M.C. Carbone,Patrizia Monteleone,Donatella Caserta,Roberto Marci,Paolo Giovanni Artini,Paola Piomboni,Riccardo Focarelli +8 more
TL;DR: It is concluded that future investigation of age-related molecular damage in the different ovarian components will be imperative in order to evaluate the possibility to save or rescue the developmental potential of aged oocytes.
Journal ArticleDOI
Antioxidant enzymatic defences in human follicular fluid: characterization and age‐dependent changes
M.C. Carbone,Carla Tatone,S. Delle Monache,Roberto Marci,Donatella Caserta,R. Colonna,Fernanda Amicarelli +6 more
TL;DR: Findings indicate that reproductive ageing is accompanied by a change in the antioxidant enzymatic pattern that could impair ROS scavenging efficiency in the follicular environment.
Journal ArticleDOI
Age-dependent changes in the expression of superoxide dismutases and catalase are associated with ultrastructural modifications in human granulosa cells.
Carla Tatone,M.C. Carbone,Stefano Falone,Pierpaolo Aimola,Annalisa Giardinelli,Donatella Caserta,Roberto Marci,Assunta Pandolfi,Anna Maria Ragnelli,Fernanda Amicarelli +9 more
TL;DR: The results indicate that GCs from older patients suffer from age-dependent oxidative stress injury and are taken as an evidence for reduced defence against reactive oxygen species (ROS) in GCs during reproductive ageing.
Journal ArticleDOI
Sirtuins in gamete biology and reproductive physiology: emerging roles and therapeutic potential in female and male infertility.
Carla Tatone,Giovanna Di Emidio,Arcangelo Barbonetti,Gaspare Carta,Alberto M. Luciano,Stefano Falone,Fernanda Amicarelli +6 more
TL;DR: Whether strategies aimed to improve Sirtuin expression or activity could have therapeutic potential for infertility associated with polycystic ovarian syndrome, endometriosis, diabetes, xenobiotic stress and aging is assessed.
Journal ArticleDOI
Cerium Oxide Nanoparticles Trigger Neuronal Survival in a Human Alzheimer Disease Model By Modulating BDNF Pathway
Barbara D'Angelo,Sandro Santucci,Elisabetta Benedetti,Silvia Di Loreto,R Phani,Stefano Falone,Fernanda Amicarelli,Maria Paola Cerù,Annamaria Cimini +8 more
TL;DR: The data obtained demonstrate that CeO2 nanoparticles do not act as mere anti-oxidant agents, but they seems to affect, directly or indirectly, signal transduction pathways involved in neuronal death and neuroprotection, raising the possibility of their use as therapeutic tools for neurodegenerative diseases.