V
Vinita Chaturvedi
Researcher at Central Drug Research Institute
Publications - 78
Citations - 2272
Vinita Chaturvedi is an academic researcher from Central Drug Research Institute. The author has contributed to research in topics: Mycobacterium tuberculosis & Antimycobacterial. The author has an hindex of 26, co-authored 75 publications receiving 1956 citations. Previous affiliations of Vinita Chaturvedi include Council of Scientific and Industrial Research.
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Thiophene containing triarylmethanes as antitubercular agents.
TL;DR: A new series of thiophene containing triarylmethane derivatives were synthesized from the Friedel-Crafts alkylation of diarylcarbinols followed by incorporation of amino alkyl chains and showed the activity in the range of 3.12-12.5 microg/mL in vitro.
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Synthesis and antitubercular screening of imidazole derivatives
Jyoti Pandey,Vinod K. Tiwari,Shyam S. Verma,Vinita Chaturvedi,Shalini Bhatnagar,Sudhir Sinha,Anil N. Gaikwad,Rama P. Tripathi +7 more
TL;DR: The synthesized imidazole based compounds screened against Mycobacterium tuberculosis where compound 17 exhibited very good in vitro antitubercular activity and may serve as a lead for further optimization.
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Application of Huisgen (3+2) cycloaddition reaction: synthesis of 1-(2,3-dihydrobenzofuran-2-yl-methyl [1,2,3]-triazoles and their antitubercular evaluations.
Rama P. Tripathi,Amit Kumar Yadav,Arya Ajay,Surendra Singh Bisht,Vinita Chaturvedi,Sudhir Sinha +5 more
TL;DR: 1,4-Disubstituted-1,2,3-triazoles (3-27) have been synthesized by [3+2] cycloaddition of different 2-(azidomethyl)-dihydronaptho(benzo)furans with different alkynes and exhibited antitubercular activities against Mycobacterium tuberculosis H37Rv.
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Evaluation of Mycobacterium smegmatis as a possible surrogate screen for selecting molecules active against multi-drug resistant Mycobacterium tuberculosis
TL;DR: The utility of M. smegmatis as a primary screen to shortlist compounds for advanced screening against MDR M. tuberculosis is highlighted and the potential of a screen based on a 'fast grower' mycobacterium to shortlisted compounds which could be active against M DR M.culosis is evaluated.
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Natural product inspired diversity oriented synthesis of tetrahydroquinoline scaffolds as antitubercular agent.
TL;DR: An efficient natural product inspired diversity oriented syn thesis of tetrahydroquinoline analogues has been developed using the natural carbohydrate derived solid acid catalyst via multicomponent aza-Diels-Alder reaction of imine with dienophile in acetonitrile in a diastereoselective manner.