V
Virginie Beray-Berthat
Researcher at Pierre-and-Marie-Curie University
Publications - 1
Citations - 959
Virginie Beray-Berthat is an academic researcher from Pierre-and-Marie-Curie University. The author has contributed to research in topics: Innate immune system & Dopaminergic. The author has an hindex of 1, co-authored 1 publications receiving 791 citations.
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Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease
Vanessa Brochard,Béhazine Combadière,Annick Prigent,Yasmina Laouar,Aline Perrin,Virginie Beray-Berthat,Olivia Bonduelle,Daniel Alvarez-Fischer,Jacques Callebert,Jean-Marie Launay,Charles Duyckaerts,Richard A. Flavell,Etienne C. Hirsch,Stéphane Hunot +13 more
TL;DR: It is shown that CD8+ and CD4+ T cells but not B cells had invaded the brain in both postmortem human PD specimens and in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of PD during the course of neuronal degeneration, and that MPTP-induced dopaminergic cell death was markedly attenuated in the absence of mature T lymphocytes.