V
Vishal Gupta
Researcher at Indian Institute of Technology Kharagpur
Publications - 25
Citations - 1106
Vishal Gupta is an academic researcher from Indian Institute of Technology Kharagpur. The author has contributed to research in topics: Biglycan & Extracellular matrix. The author has an hindex of 14, co-authored 25 publications receiving 1010 citations. Previous affiliations of Vishal Gupta include Rice University & Wayne State University.
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Journal ArticleDOI
Effects of static and cyclic loading in regulating extracellular matrix synthesis by cardiovascular cells
TL;DR: In vitro modulation of the synthesis of various ECM molecules through static or cyclic stretching of cardiovascular cells is investigated to enhance the understanding of ECM regulation and pathologies.
Journal ArticleDOI
Quantifying influenza vaccine efficacy and antigenic distance.
TL;DR: In this paper, a new measure of antigenic distance between influenza A vaccine and circulating strains was introduced, which correlated with vaccine efficacy to a greater degree than are current state of the art phylogenetic sequence analyses or ferret antisera inhibition assays.
Journal ArticleDOI
Glycosaminoglycans and proteoglycans in normal mitral valve leaflets and chordae: association with regions of tensile and compressive loading.
K. Jane Grande-Allen,Anthony Calabro,Vishal Gupta,Thomas N. Wight,Vincent C. Hascall,Ivan Vesely +5 more
TL;DR: The relative amounts and distributions of these GAGs are consistent with the tensile and compressive loads that these tissues bear, and many different chondroitin/dermatan sulfate subclasses were significantly decreased with advancing age.
Posted Content
Quantifying Influenza Vaccine Efficacy and Antigenic Distance
TL;DR: A new measure of antigenic distance is introduced that correlates well with efficacies of the H3N2 influenza A component of the annual vaccine between 1971 and 2004 and with results of a theory of the immune response to influenza following vaccination.
Journal ArticleDOI
Abundance and location of proteoglycans and hyaluronan within normal and myxomatous mitral valves
Vishal Gupta,Janet E. Barzilla,Joe S. Mendez,Elizabeth H. Stephens,Elaine L. Lee,C. David Collard,Rodolfo Laucirica,Paul H. Weigel,Kathryn Jane Grande-Allen +8 more
TL;DR: Excess decorin, biglycan, and versican may be associated with the remodeling of other matrix components in myxomatous mitral valve disease and developing potential new therapies.