V
Vishnu Dwivedi
Researcher at Allahabad University
Publications - 7
Citations - 208
Vishnu Dwivedi is an academic researcher from Allahabad University. The author has contributed to research in topics: Curcumin & Binding site. The author has an hindex of 5, co-authored 7 publications receiving 186 citations.
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Journal ArticleDOI
Curcumin recognizes a unique binding site of tubulin.
Soumyananda Chakraborti,Lalita Das,Neha Kapoor,Amlan Das,Vishnu Dwivedi,Asim Poddar,Gopal Chakraborti,Mark E. Janik,Gautam Basu,Dulal Panda,Pinak Chakrabarti,Avadhesha Surolia,Bhabatarak Bhattacharyya +12 more
TL;DR: Using fluorescence spectroscopy, it is shown that curcumin binds tubulin 32 Å away from the colchicine-binding site, and structure-activity studies suggest that the tridented nature of compound 7 is responsible for its higher affinity for tubulin compared toCurcumin.
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Stable and potent analogues derived from the modification of the dicarbonyl moiety of curcumin
Soumyananda Chakraborti,Gopa Dhar,Vishnu Dwivedi,Amlan Das,Asim Poddar,Gopal Chakraborti,Gautam Basu,Pinak Chakrabarti,Avadhesha Surolia,Bhabatarak Bhattacharyya +9 more
TL;DR: It is found that curcumin also loses its activity instantaneously in a reducing environment, and results strongly suggest that compounds 2 and 3 could be good replacements forCurcumin in future drug development.
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Telomerase targeted anticancer bioactive prodrug by antisense-based approach.
TL;DR: This DNA-curcumin-tetraglycine acts as a prodrug being targeted by antisense mechanism to telomerase, and is found to affect cell growth in the former.
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Benzothiophene carboxamide derivatives as inhibitors of Plasmodium falciparum enoyl-ACP reductase.
Tanushree Banerjee,Shailendra Kumar Sharma,Neha Kapoor,Vishnu Dwivedi,Namita Surolia,Avadhesha Surolia +5 more
TL;DR: Bromo‐benzothiophene carboxamide derivatives as potent, slow tight binding inhibitors of Plasmodium enoyl‐acyl carrier protein (ACP) reductase (PfENR) hold promise for the development of potent antimalarials.
Journal ArticleDOI
Novel Method for Preparation of Monoesters of Symmetric Diphenolic Compounds like Curcumin (1,7‐Bis(4‐hydroxy‐3‐methoxy phenyl)‐1,6‐heptadiene‐3,5‐dione) via Solid‐Phase Synthesis
TL;DR: In this article, a monoester of curcumin was synthesized by anchoring one of its free phenolic groups to an insoluble polymeric solid-support resin controlled pore glass-long chain alkylamine via a 2-carbon linker by solid phase synthesis.