N
Neha Kapoor
Researcher at Hindu College, University of Delhi
Publications - 26
Citations - 417
Neha Kapoor is an academic researcher from Hindu College, University of Delhi. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 8, co-authored 19 publications receiving 319 citations. Previous affiliations of Neha Kapoor include Allahabad University & Indian Institute of Science.
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Curcumin recognizes a unique binding site of tubulin.
Soumyananda Chakraborti,Lalita Das,Neha Kapoor,Amlan Das,Vishnu Dwivedi,Asim Poddar,Gopal Chakraborti,Mark E. Janik,Gautam Basu,Dulal Panda,Pinak Chakrabarti,Avadhesha Surolia,Bhabatarak Bhattacharyya +12 more
TL;DR: Using fluorescence spectroscopy, it is shown that curcumin binds tubulin 32 Å away from the colchicine-binding site, and structure-activity studies suggest that the tridented nature of compound 7 is responsible for its higher affinity for tubulin compared toCurcumin.
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Differential apoptotic and redox regulatory activities of curcumin and its derivatives.
Satyendra Mishra,Neha Kapoor,A. Mubarak Ali,B.V.V. Pardhasaradhi,A. Leela Kumari,Ashok Khar,Krishna Misra +6 more
TL;DR: The apoptotic activity of these derivatives correlated very well with the generation of ROS by the tumor cells, whereas GSH levels remained unaltered.
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Therapeutic attributes and applied aspects of biological macromolecules (polypeptides, fucoxanthin, sterols, fatty acids, polysaccharides, and polyphenols) from diatoms - A review.
Archana Tiwari,Elda M. Melchor-Martínez,Abhishek Saxena,Neha Kapoor,Kawal Jeet Singh,Sara Saldarriaga-Hernandez,Roberto Parra-Saldívar,Hafiz M.N. Iqbal +7 more
TL;DR: In this paper, the authors highlight the notable applications of diatoms and their biologically active constituents, such as fucoxanthin and omega 3 fatty acids, among others with unique structural and functional entities.
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Structural basis for the functional and inhibitory mechanisms of β-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Plasmodium falciparum.
Koustav Maity,Bharat Somireddy Venkata,Neha Kapoor,Namita Surolia,Avadhesha Surolia,Kaza Suguna +5 more
TL;DR: The crystal structures of the complexes of PfFabZ provides the structural basis of the inhibitory mechanism of the enzyme that could be used to improve the potency of inhibitors against an important component of fatty acid synthesis common to many infectious organisms.
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Telomerase targeted anticancer bioactive prodrug by antisense-based approach.
TL;DR: This DNA-curcumin-tetraglycine acts as a prodrug being targeted by antisense mechanism to telomerase, and is found to affect cell growth in the former.