V
Vivi Kasim
Researcher at Chongqing University
Publications - 49
Citations - 1347
Vivi Kasim is an academic researcher from Chongqing University. The author has contributed to research in topics: Medicine & Carcinogenesis. The author has an hindex of 15, co-authored 32 publications receiving 997 citations. Previous affiliations of Vivi Kasim include University of Tokyo.
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Journal ArticleDOI
An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA
Yoshiko Maida,Mami Yasukawa,Miho Furuuchi,Timo Lassmann,Richard Possemato,Naoko Okamoto,Vivi Kasim,Yoshihide Hayashizaki,William C. Hahn,William C. Hahn,Kenkichi Masutomi +10 more
TL;DR: It is shown that TERT interacting with the RNA component of mitochondrial RNA processing endoribonuclease (RMRP), a gene that is mutated in the inherited pleiotropic syndrome cartilage–hair hypoplasia, identifies a mammalian RdRP composed of TERT in complex with RMRP.
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Maintenance of tumor initiating cells of defined genetic composition by nucleostemin
Naoko Okamoto,Mami Yasukawa,Christine L. Nguyen,Vivi Kasim,Yoshiko Maida,Richard Possemato,Tatsuhiro Shibata,Keith L. Ligon,Kiyoko Fukami,William C. Hahn,Kenkichi Masutomi +10 more
TL;DR: It is shown that overexpression of either of the nucleolar GTP-binding proteins nucleostemin (NS) or GNL3L drives the fraction of genetically defined tumor cells that exhibit markers and tumorigenic properties of TICs.
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Continuous Cell Partitioning Using an Aqueous Two-Phase Flow System in Microfluidic Devices
TL;DR: This microscale aqueous two-phase flow system can be incorporated into micro total analysis systems (microTAS) or lab-on-a-chip technology, owing to its simplicity, applicability, and biocompatibility.
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Transcription Factor YY1 Promotes Cell Proliferation by Directly Activating the Pentose Phosphate Pathway
Shourong Wu,Hui-Min Wang,Yanjun Li,Yu-Dan Xie,Can Huang,Hezhao Zhao,Makoto Miyagishi,Vivi Kasim +7 more
TL;DR: It is shown that YY1 alters tumor cell metabolism by activating glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme in the pentose phosphate pathway, which links its function in tumorigenesis to metabolic reprogramming in tumor cells.
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Control of siRNA expression using the Cre–loxP recombination system
TL;DR: A system for controlling the U6 promoter-driven expression of siRNA using the Cre-loxP recombination system and a 'Cre-On' siRNA expression vector, which could be switched on upon excision catalyzed by Cre recombinase, and delivered to cells directly from the medium as a fusion protein.