V
Vivianne C. G. Tjan-Heijnen
Researcher at Maastricht University
Publications - 267
Citations - 12390
Vivianne C. G. Tjan-Heijnen is an academic researcher from Maastricht University. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 51, co-authored 244 publications receiving 9764 citations. Previous affiliations of Vivianne C. G. Tjan-Heijnen include Maastricht University Medical Centre & Radboud University Nijmegen.
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Journal ArticleDOI
Update on Prevalence of Pain in Patients With Cancer: Systematic Review and Meta-Analysis
Marieke H. J. van den Beuken-van Everdingen,Laura M.J. Hochstenbach,Elbert A.J. Joosten,Vivianne C. G. Tjan-Heijnen,Daisy J.A. Janssen +4 more
TL;DR: Despite increased attention on assessment and management, pain continues to be a prevalent symptom in patients with cancer and in the upcoming decade, the authors need to overcome barriers toward effective pain treatment and develop and implement interventions to optimally manage pain in Patients with cancer.
Journal ArticleDOI
2010 update of EORTC guidelines for the use of granulocyte-colony stimulating factor to reduce the incidence of chemotherapy-induced febrile neutropenia in adult patients with lymphoproliferative disorders and solid tumours
Matti Aapro,Julia Bohlius,David Cameron,Lissandra Dal Lago,J. Peter Donnelly,Nora Kearney,Gary H. Lyman,Ruth Pettengell,Vivianne C. G. Tjan-Heijnen,Jan Walewski,Damien C. Weber,Christoph C. Zielinski +11 more
TL;DR: Clinical evidence shows that filgrastim, lenograstim and pegfilgrastIM have clinical efficacy and the use of any of these agents to prevent FN and FN-related complications where indicated and prophylactic G-CSF support is recommended.
Journal ArticleDOI
Randomized Controlled Trial of Resection Versus Radiotherapy After Induction Chemotherapy in Stage IIIA-N2 Non–Small-Cell Lung Cancer
Jan P. van Meerbeeck,Gijs W. P. M. Kramer,Paul Van Schil,Catherine Legrand,Egbert F. Smit,Franz M.N.H. Schramel,Vivianne C. G. Tjan-Heijnen,Bonne Biesma,C. Debruyne,Nico van Zandwijk,Ted A.W. Splinter,Giuseppe Giaccone +11 more
TL;DR: In selected patients with pathologically proven stage IIIA-N2 NSCLC and a response to induction chemotherapy, surgical resection did not improve overall or progression-free survival compared with radiother- apy, and radiotherapy should be considered the preferred locoregional treatment for these patients.
Journal ArticleDOI
Pan-cancer whole-genome analyses of metastatic solid tumours
Peter Priestley,Jonathan Baber,Martijn P. Lolkema,Neeltje Steeghs,Ewart de Bruijn,Charles Shale,Korneel Duyvesteyn,Susan Haidari,Arne Van Hoeck,Wendy Onstenk,Paul Roepman,Mircea Voda,Haiko J. Bloemendal,Vivianne C. G. Tjan-Heijnen,Carla M.L. van Herpen,Mariette Labots,Petronella O. Witteveen,Egbert F. Smit,Stefan Sleijfer,Emile E. Voest,Edwin Cuppen +20 more
TL;DR: The largest, to the authors' knowledge, pan-cancer study of metastatic solid tumour genomes, including whole-genome sequencing data for 2,520 pairs of tumour and normal tissue pairs, analysed at median depths of 106× and 38×, respectively, and surveying more than 70 million somatic variants is described.
Journal ArticleDOI
Micrometastases or Isolated Tumor Cells and the Outcome of Breast Cancer
Maaike de Boer,Carolien H.M. van Deurzen,Jos A.A.M. van Dijck,George F. Borm,Paul J. van Diest,Eddy M. M. Adang,Johan W.R. Nortier,Emiel J. Th. Rutgers,Caroline Seynaeve,Marian B. E. Menke-Pluymers,Peter Bult,Vivianne C. G. Tjan-Heijnen +11 more
TL;DR: Isolated tumor cells or micrometastases in regional lymph nodes were associated with a reduced 5-year rate of disease-free survival among women with favorable early-stage breast cancer who did not receive adjuvant therapy.