V
Vladimir B. Serikov
Researcher at Children's Hospital Oakland Research Institute
Publications - 39
Citations - 3423
Vladimir B. Serikov is an academic researcher from Children's Hospital Oakland Research Institute. The author has contributed to research in topics: Mesenchymal stem cell & Lung. The author has an hindex of 19, co-authored 39 publications receiving 3138 citations. Previous affiliations of Vladimir B. Serikov include Children's Hospital Oakland & Russian Academy of Sciences.
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Journal ArticleDOI
Intrapulmonary Delivery of Bone Marrow-Derived Mesenchymal Stem Cells Improves Survival and Attenuates Endotoxin-Induced Acute Lung Injury in Mice
TL;DR: Treatment with intrapulmonary MSC markedly decreases the severity of endotoxin-induced acute lung injury and improves survival in mice.
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Antibacterial Effect of Human Mesenchymal Stem Cells Is Mediated in Part from Secretion of the Antimicrobial Peptide LL‐37
Anna Krasnodembskaya,Yuanlin Song,Xiaohui Fang,Naveen Gupta,Vladimir B. Serikov,Jae-Woo Lee,Michael A. Matthay +6 more
TL;DR: Human bone marrow‐derived MSCs possess direct antimicrobial activity, which is mediated in part by the secretion of human cathelicidin hCAP‐18/ LL‐37, analysis of expression of major antimicrobial peptides indicated.
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Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung.
TL;DR: Treatment with allogeneic human MSCs or the conditioned medium restores normal fluid balance in an ex vivo perfused human lung injured by E. coli endotoxin.
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Mesenchymal stem cells enhance survival and bacterial clearance in murine Escherichia coli pneumonia
Naveen Gupta,Anna Krasnodembskaya,Maria G. Kapetanaki,Majd Mouded,Xinping Tan,Vladimir B. Serikov,Michael A. Matthay +6 more
TL;DR: Treatment with MSCs enhanced survival and bacterial clearance in a mouse model of Gram-negative pneumonia and enhanced bacterial clearance from the alveolar space as early as 4 h after administration, an effect that was not observed with the other treatment groups.
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Potential application of mesenchymal stem cells in acute lung injury
TL;DR: The existing experimental literature that has tested the use of MSC in models of ALI/ARDS is described, and the potential mechanisms underlying their therapeutic use are described with an emphasis on secreted paracrine soluble factors.