V
Vojtěch Škop
Researcher at National Institutes of Health
Publications - 6
Citations - 180
Vojtěch Škop is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Thermoregulation & Preoptic area. The author has an hindex of 4, co-authored 6 publications receiving 73 citations.
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Journal ArticleDOI
Mouse Thermoregulation: Introducing the Concept of the Thermoneutral Point.
TL;DR: In mice, there was no ambient temperature zone where both metabolic rate and body temperature were constant, and the concept of a thermoneutral point (TNP) was proposed, a discrete ambient temperature below which energy expenditure increases and above which body temperature increases.
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Brs3 neurons in the mouse dorsomedial hypothalamus regulate body temperature, energy expenditure, and heart rate, but not food intake.
Ramón A. Piñol,Sebastian H. Zahler,Chia Li,Atreyi Saha,Brandon K. Tan,Vojtěch Škop,Oksana Gavrilova,Cuiying Xiao,Michael J. Krashes,Marc L. Reitman +9 more
TL;DR: It is found that the preoptic area provides major input (excitatory and inhibitory) to DMHBrs3 neurons, and Brs3 neurons in the paraventricular nucleus of the hypothalamus regulate food intake, suggesting a necessary role in Tb regulation.
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Preoptic BRS3 neurons increase body temperature and heart rate via multiple pathways.
Ramón A. Piñol,Allison S. Mogul,Colleen K. Hadley,Atreyi Saha,Chia Li,Vojtěch Škop,Haley S. Province,Cuiying Xiao,Oksana Gavrilova,Michael J. Krashes,Marc L. Reitman +10 more
TL;DR: The preoptic area (POA) is a key brain region for regulation of body temperature (Tb), dictating thermogenic, cardiovascular, and behavioral responses that control Tb as discussed by the authors.
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The contribution of the mouse tail to thermoregulation is modest
TL;DR: The mouse tail is a useful biomarker of vasodilation and thermoregulation, but in the authors' experiments contributes only 5-8 % of whole-body heat dissipation, less than the 17 % reported for rat.
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The effects of housing density on mouse thermal physiology depend on sex and ambient temperature.
TL;DR: In this article, the effects of housing density on mouse thermal physiology in both sexes were quantified by indirect calorimetry with continuous measurement of core body temperature, energy expenditure, physical activity, and food intake.