W
Wai Hoe Ng
Researcher at National University of Singapore
Publications - 118
Citations - 2880
Wai Hoe Ng is an academic researcher from National University of Singapore. The author has contributed to research in topics: Glioma & Temozolomide. The author has an hindex of 29, co-authored 113 publications receiving 2475 citations. Previous affiliations of Wai Hoe Ng include Boston Children's Hospital & Toronto Western Hospital.
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Human bone marrow-derived mesenchymal stem cells suppress human glioma growth through inhibition of angiogenesis.
TL;DR: The results showed that MSC inhibited the growth of humanglioma cell lines and patient‐derived primary glioma cells in vitro, and indicated that the antitumor effect of MSC may be mediated through downregulation of PDGF/PDGFR axis, which is known to play a key role in gliomas angiogenesis.
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Diffusion-weighted MR imaging: diagnosing atypical or malignant meningiomas and detecting tumor dedifferentiation.
TL;DR: In this paper, the utility of diffusion-weighted (DW) MR imaging to differentiate atypical/malignant from benign meningiomas and to detect histologic dedifferentiation to higher tumor grade was investigated.
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Matrix metalloproteinase 1 is necessary for the migration of human bone marrow-derived mesenchymal stem cells toward human glioma.
Ivy A.W. Ho,Kelly Y. W. Chan,Wai Hoe Ng,Chang M. Guo,Kam M. Hui,Philip Cheang,Paula Y.P. Lam +6 more
TL;DR: Supporting evidence is provided for the first time that M MP1 is critically involved in the migration capacity of MSCs, acting through the MMP1/PAR1 axis.
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Comparison of magnetic resonance spectroscopy and perfusion-weighted imaging in presurgical grading of oligodendroglial tumors.
Maosheng Xu,Siew Ju See,Wai Hoe Ng,Earnest Arul,Michael Back,Tseng Tsai Yeo,C. C. Tchoyoson Lim +6 more
TL;DR: MRSI measurements are more accurate than perfusion-weighted magnetic resonance imaging or conventional contrast enhancement in differentiating oligodendroglial tumor grade in these inherently vascular tumors and may be better than measures of neovascularity in presurgical grading.
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Augmented reality neurosurgical planning and navigation for surgical excision of parasagittal, falcine and convexity meningiomas.
TL;DR: The use of the Dextroscope for pre-operative surgical planning allows for appreciation of complex anatomical relationships in 3D and is further translated for use during surgical navigation utilizing the DEX-Ray platform that provided the superior advantage of allowing fast and accurate surgical resection confidently.