W
Walter E. Finkbeiner
Researcher at University of California, San Francisco
Publications - 180
Citations - 12061
Walter E. Finkbeiner is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Cystic fibrosis transmembrane conductance regulator & Cystic fibrosis. The author has an hindex of 55, co-authored 176 publications receiving 11364 citations. Previous affiliations of Walter E. Finkbeiner include University of California, Berkeley & University of California, Davis.
Papers
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Journal ArticleDOI
CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells.
A. L. Cozens,M. J. Yezzi,Karl Kunzelmann,T. Ohrui,Leslie Y. M. Chin,Kevin Eng,Walter E. Finkbeiner,Jonathan Widdicombe,Dieter C. Gruenert +8 more
TL;DR: The successful establishment of a postcrisis SV40 large T-antigen transformed epithelial cell line derived from human bronchial epithelium is described, and this cell line, 16HBE14o- cells, provides a valuable resource for studying the modulation of CFTR and its role in regulation of chloride ion transport in human airway epithelia as well as other aspects of human airways cell biology.
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Autopsy findings in the acquired immune deficiency syndrome.
Kevin Welch,Walter E. Finkbeiner,Charles E. Alpers,Walter Blumenfeld,Richard L. Davis,Edward A. Smuckler,Jay H. Beckstead +6 more
TL;DR: The most consistent and striking autopsy finding was a severe depletion of lymphoid tissues, which was attributable to opportunistic infections affecting most commonly the respiratory tract and meninges.
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Differentiated structure and function of cultures from human tracheal epithelium
TL;DR: The conditions which allow cultured human tracheal epithelial cells to retain the ion transport properties and ultrastructure of the original tissue are described and an air interface (AIR) gave better electrical properties than immersion feeding (IMM).
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Calu-3: a human airway epithelial cell line that shows cAMP-dependent Cl- secretion
TL;DR: Of 12 cell lines derived from human lung cancers, only Calu-3 cells showed high transepithelial resistance (Rte) and increases in short-circuit current (Isc) in response to mediators, and it is anticipated that Calu -3 cells will prove useful in the study of Cl- secretion and other functions of human airway epithelial cells.
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Ozone-induced airway inflammation in human subjects as determined by airway lavage and biopsy
TL;DR: Morphometry demonstrated that O3 exposure induced an acute inflammatory cell influx into the airway in addition to that previously documented to occur in the distal lung.