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Walter M. Stadler

Researcher at University of Chicago

Publications -  513
Citations -  37554

Walter M. Stadler is an academic researcher from University of Chicago. The author has contributed to research in topics: Cancer & Prostate cancer. The author has an hindex of 88, co-authored 494 publications receiving 34323 citations. Previous affiliations of Walter M. Stadler include Cleveland Clinic & Northwestern University.

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Phase I study of doxorubicin (D) plus anti-insulin-like growth factor 1 receptor (IGF-1R) antibody cixutumumab (IMC-A12) in advanced soft tissue sarcoma (STS).

TL;DR: A dose escalation study of C with D in STS, where anti-IGF1R antibody cixutumumab has shown acceptable toxicity in a single-agent phase 2 study of STS and the TITE-CRM method was used to estimate the probability of DLT at each dose level.
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A phase II trial of gemcitabine(G), capecitabine (C), and bevacizumab (B) in patients (pts) with metastatic renal cell carcinoma (RCC)

TL;DR: The trial was terminated early despite not meeting protocol criteria for success or futility due to slow accrual and the fact that the historical response rate on which the trial was based became irrelevant with emerging data using sequential VEGF pathway directed therapies.