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Walter Pirker
Researcher at Medical University of Vienna
Publications - 87
Citations - 5736
Walter Pirker is an academic researcher from Medical University of Vienna. The author has contributed to research in topics: Parkinson's disease & Dopaminergic. The author has an hindex of 36, co-authored 79 publications receiving 5127 citations. Previous affiliations of Walter Pirker include University of Vienna.
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Journal ArticleDOI
A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease
Alexander Zimprich,Anna Benet-Pagès,Walter Struhal,Elisabeth Graf,Sebastian H. Eck,Marc N. Offman,Dietrich Haubenberger,Sabine Spielberger,Eva C. Schulte,Peter Lichtner,Shaila C. Rossle,Norman Klopp,Elisabeth Wolf,Klaus Seppi,Walter Pirker,Stefan Presslauer,Brit Mollenhauer,Regina Katzenschlager,Thomas Foki,Christoph Hotzy,Eva M. Reinthaler,Ashot S. Harutyunyan,Robert Kralovics,Annette Peters,Fritz Zimprich,Thomas Brücke,Werner Poewe,Eduard Auff,Claudia Trenkwalder,Burkhard Rost,Gerhard Ransmayr,Juliane Winkelmann,Thomas Meitinger,Tim M. Strom +33 more
TL;DR: An Austrian family with 16 affected individuals by exome sequencing found a missense mutation, c.1858G>A (p.Asp620Asn), in the VPS35 gene in all seven affected family members who are alive, and found the same variant cosegregating with the disease in an autosomal-dominant mode with high but incomplete penetrance.
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The Onset of Nonmotor Symptoms in Parkinson's disease (The ONSET PD Study)
Claustre Pont-Sunyer,Anna Hotter,Carles Gaig,Klaus Seppi,Yaroslau Compta,Regina Katzenschlager,Natalia Mas,Dominik Hofeneder,Thomas Brücke,Àngels Bayés,Karoline Wenzel,Jon Infante,Heidemarie Zach,Walter Pirker,Ignacio J. Posada,Ramiro Álvarez,Lourdes Ispierto,Oriol De Fabregues,Antoni Callén,Antoni Palasí,Miquel Aguilar,María José Martí,Francesc Valldeoriola,Manel Salamero,Werner Poewe,Eduardo Tolosa +25 more
TL;DR: Nonmotor symptoms (NMS) in Parkinson's disease (PD) are common in early unmedicated PD and frequently reported to occur in the premotor period, but a patient subgroup showed high NMS burden mainly resulting from cognition‐related symptoms.
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Gait disorders in adults and the elderly : A clinical guide.
TL;DR: This clinically oriented review provides an overview on the phenotypic spectrum, work-up and treatment of gait disorders.
Journal ArticleDOI
Correlation of dopamine transporter imaging with parkinsonian motor handicap: how close is it?
TL;DR: Available data suggest that putamen [18F]fluorodopa uptake, when compared with striatal DAT binding, may be more closely related to parkinsonian motor handicap.
Journal ArticleDOI
[123I]β-CIT SPECT in multiple system atrophy, progressive supranuclear palsy, and corticobasal degeneration
Walter Pirker,Susanne Asenbaum,Gerhard Bencsits,Daniela Prayer,Willibald Gerschlager,Lüder Deecke,Thomas Brücke +6 more
TL;DR: In conclusion, [123I]β‐CIT SPECT reliably enables the visualization of the presynaptic dopaminergic lesion in patients with MSA, PSP, and CBD.