W
Wang Zhou
Researcher at Second Military Medical University
Publications - 52
Citations - 1705
Wang Zhou is an academic researcher from Second Military Medical University. The author has contributed to research in topics: Stromal cell & Survival rate. The author has an hindex of 21, co-authored 48 publications receiving 1412 citations. Previous affiliations of Wang Zhou include Tsinghua University.
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The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes
Hao Zhang,Zijian Kang,Haiyi Gong,Da Xu,Jing Wang,Zifu Li,Xingang Cui,Jianru Xiao,Tong Meng,Wang Zhou,Jianmin Liu,Huji Xu,Huji Xu +12 more
TL;DR: The bioinformatics evidence of the potential route for infection of 2019-nCov in digestive system along with respiratory tract is provided and may have significant impact for the authors' healthy policy setting regards to prevention of2019-nCoV infection.
Posted ContentDOI
The insert sequence in SARS-CoV-2 enhances spike protein cleavage by TMPRSS
Tong Meng,Cao H,Cao H,Hongwei Zhang,Zijian Kang,Da Xu,Haiyi Gong,Jing Wang,Zhixuan Li,Xingang Cui,Huji Xu,Huji Xu,Haifeng Wei,Xiu-Wu Pan,Ruixin Zhu,Jianru Xiao,Wang Zhou,Cheng L,Jianmin Liu +18 more
TL;DR: The bioinformatics evidence for the increased spike protein cleavage of SARS-CoV-2 is provided and its potential target cells are indicated, including esophageal upper epithelial cells and absorptive enterocytes.
Journal ArticleDOI
Hypoxia activates Wnt/β-catenin signaling by regulating the expression of BCL9 in human hepatocellular carcinoma.
Wei Xu,Wang Zhou,Mo Cheng,Jing Wang,Jing Wang,Zhi’an Liu,Shaohui He,Xiangji Luo,Wending Huang,Tianrui Chen,Wangjun Yan,Wangjun Yan,Jianru Xiao +12 more
TL;DR: It is found that hypoxia may promote the expression of BCL9 and associate with the development of HCC, and specific regulation of B CL9 expression by HIF-1α may prove to be an underlying crosstalk between Wnt/β-catenin signaling and hypoxIA signaling pathways.
Journal ArticleDOI
Clinical features and prognostic factors of patients with chordoma in the spine: a retrospective analysis of 153 patients in a single center.
Tong Meng,Huabin Yin,Bo Li,Zhenxi Li,Wei Xu,Wang Zhou,Mo Cheng,Jing Wang,Lei Zhou,Xinghai Yang,Tielong Liu,Wangjun Yan,Dianwen Song,Jianru Xiao +13 more
TL;DR: Total spondylectomy, by either en bloc or piecemeal method, could significantly reduce local relapse-free survival (LRFS) for spinal chordoma patients.
Posted ContentDOI
The transmembrane serine protease inhibitors are potential antiviral drugs for 2019-nCoV targeting the insertion sequence-induced viral infectivity enhancement
Tong Meng,Hao Cao,Hao Cao,Hao Zhang,Zijian Kang,Da Xu,Haiyi Gong,Jing Wang,Zifu Li,Xingang Cui,Huji Xu,Huji Xu,Haifeng Wei,Xiu-Wu Pan,Rongrong Zhu,Jianru Xiao,Wang Zhou,Liming Cheng,Jianmin Liu +18 more
TL;DR: Transmembrane serine protease inhibitors as the antiviral treatment options for 2019-nCoV infection targeting TMPRSS2 are indicated and bioinformatics and structure evidence for the increased viral infectivity of 2019- nCoV is provided.