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Wei-Chih Chao
Researcher at Fu Jen Catholic University
Publications - 16
Citations - 360
Wei-Chih Chao is an academic researcher from Fu Jen Catholic University. The author has contributed to research in topics: Water environment & Hydrogen bond. The author has an hindex of 8, co-authored 15 publications receiving 255 citations. Previous affiliations of Wei-Chih Chao include National Taiwan University.
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Journal ArticleDOI
Snapshotting the Excited-State Planarization of Chemically Locked N,N′-Disubstituted Dihydrodibenzo[a,c]phenazines
Wei Chen,Chi-Lin Chen,Zhiyun Zhang,Zhiyun Zhang,Yi-An Chen,Wei-Chih Chao,Jianhua Su,He Tian,Pi-Tai Chou +8 more
TL;DR: A tailored strategy to harness the excited-state planarization of N,N'-disubstituted dihydrodibenzo[a,c]phenazines by halting the structural evolution via a macrocyclization process is exploited, showing the brightening prospect of these chemically locked DPAC-n in both fundamental studies and applications.
Journal ArticleDOI
Probing water micro-solvation in proteins by water catalysed proton-transfer tautomerism
Jiun-Yi Shen,Wei-Chih Chao,Chun Liu,Hsiao-An Pan,Hsiao-Ching Yang,Chi-Lin Chen,Chi-Lin Chen,Yi-Kang Lan,Li-Ju Lin,Jinn-Shyan Wang,Jyh-Feng Lu,Steven Chun-Wei Chou,Kuo-Chun Tang,Pi-Tai Chou +13 more
TL;DR: A tryptophan analogue is presented that exhibits remarkable water catalysed proton-transfer properties and provides unique fingerprints that can be exploited for direct sensing of a site-specific water environment in a protein without disrupting its native structure.
Journal ArticleDOI
High efficiency green InP quantum dot light-emitting diodes by balancing electron and hole mobility
Wei-Chih Chao,Tzu-Hsuan Chiang,Yi-Chun Liu,Zhi-Xuan Huang,Chia-Chun Liao,Chen-Hsien Chu,Chih-Hsing Wang,Huan-Wei Tseng,Wen-Yi Hung,Pi-Tai Chou +9 more
TL;DR: In this paper, green InP quantum dots are prepared and incorporated into a QLED so to promote hole transport and reduce electron mobility, resulting in a maximum quantum efficiency of 16.3 %.
Journal ArticleDOI
Flavonoids from Gynostemma pentaphyllum Exhibit Differential Induction of Cell Cycle Arrest in H460 and A549 Cancer Cells
Ko-Chung Tsui,Tzu-Hsuan Chiang,Jinn-Shyan Wang,Li-Ju Lin,Wei-Chih Chao,Bing-Huei Chen,Jyh-Feng Lu +6 more
TL;DR: It is strongly suggested that the growth inhibition discrepancy between H460 and A549 following flavonoid treatment can be attributed to the lack of cell cycle arrest in H460 cells and the differences between H 460 and A550 cells may serve as contrasting models for further mechanistic investigations.
Journal ArticleDOI
Induction of p53-independent growth inhibition in lung carcinoma cell A549 by gypenosides.
Jung-Sen Liu,Tzu-Hsuan Chiang,Jinn-Shyan Wang,Li-Ju Lin,Wei-Chih Chao,Baskaran Stephen Inbaraj,Jyh-Feng Lu,Bing-Huei Chen +7 more
TL;DR: Saponin fraction, which consisted mainly of gypenoside (Gyp) XXII and XXIII, rather than the carotenoid and chlorophyll ones, was effective in inhibiting A549 cell growth in a concentration‐ and a time‐dependent manner, and the cell cycle arrest and apoptosis of A549 cells induced by Gyp would most likely proceed through p53‐independent pathway(s).