Wei Li

TL;DR: In this paper, the authors summarized the known pathological axes of chronic low back pain (CLBP), involving both peripheral and central systems, and detailed injurious nerve stimulation, inflammation-induced peripheral pathway, and central sensitization.

TL;DR: The energy sensor adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) and its agonist berberine can combat the common underlying pathological events of neurodegeneration including oxidative stress, neuroinflammation, mitochondrial disorder, glutamate excitotoxicity, apoptosis, autophagy disorder and neurovascular units disruption.

TL;DR: Parkinson's disease (PD) is a chronic and progressive neurodegenerative disease caused by degeneration of dopaminergic neurons in the substantia nigra as discussed by the authors, which can be treated with acupuncture.

TL;DR: Several studies demonstrated that the agonists of orexin might be effective in the treatment of DOC, providing novel therapeutic opportunities in this field of TBI-induced DOC.

TL;DR: The combination of acupuncture and MSCs transplantation could become a novel and effective strategy for the treatment of SCI and needs to be verified by basic and clinical research.