Wei Lu

TL;DR: Helicobacter pylori eradication rates with standard triple therapy are declining worldwide, and new treatment combinations for antibiotic resistant H.pylori strains are required, especially for patients with penicillin allergy.

TL;DR: Results indicate that a discrete surface of the urease complex is important for H. pylori persistence during gastric colonisation, and it is proposed that this surface interacts directly with host components important for the host-pathogen interaction, immune modulation or other actions that underlie H.pylora persistence in its special gastric mucosal niche.

TL;DR: It is shown that there is diversity in bacterial cell surface area and surface hydrophobicity within N. meningitidis which influence steps in meningococcal pathogenesis.

TL;DR: It is shown that small amounts of HcpA cause the transition of round‐shaped monocytes into cells with star‐like morphologies, adherence to the culture dish surface, and expression of the surface marker protein CD11b, all of which are indicative of a macrophage‐like phenotype.

TL;DR: The results suggest that Sahul64, with the absence of cagPAI, highly divergent cell envelope proteins, and a predicted nontransportable VacA protein, could be more highly adapted to ancient indigenous Australian people but with lower virulence potential compared to other sequenced and cag PAI-positive H. pylori strains.