W
Weida Gong
Researcher at University of North Carolina at Chapel Hill
Publications - 34
Citations - 589
Weida Gong is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 6, co-authored 19 publications receiving 184 citations. Previous affiliations of Weida Gong include Xiamen University.
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Journal ArticleDOI
Estimation of 18S Gene Copy Number in Marine Eukaryotic Plankton Using a Next-Generation Sequencing Approach
Weida Gong,Adrian Marchetti +1 more
TL;DR: A computational method is used to estimate 18S gene copy number in seven species of marine eukaryotic phytoplankton and found strong interspecies and strain-level differences across and within the examined species.
Journal ArticleDOI
Molecular insights into a dinoflagellate bloom.
TL;DR: Under bloom conditions, there is increased expression of metabolic pathways indicative of rapidly growing cells, including energy production, carbon metabolism, transporters and synthesis of cellular membrane components, and there is a prominence of highly expressed genes involved in the synthesis of membrane-associated molecules.
Journal ArticleDOI
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis
Jun Wang,Xufen Yu,Weida Gong,Xijuan Liu,Kwang-Su Park,Anqi Ma,Yi-Hsuan Tsai,Yu-Ming Shen,Takashi Onikubo,Wenhu Pi,David F. Allison,Jing Liu,Wei-Yi Chen,Lin Cai,Robert G. Roeder,Jian Jin,Gang Wang +16 more
TL;DR: Zhang et al. as mentioned in this paper reported that EZH2 has additional non-canonical functions by binding cMyc at non-PRC2 targets and uses a hidden transactivation domain (TAD) for (co)activator recruitment and gene activation.
Journal ArticleDOI
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis
Jun Wang,Xufen Yu,Weida Gong,Xijuan Liu,Kwang-Su Park,Anqi Ma,Yi-Hsuan Tsai,Yu-Ming Shen,Takashi Onikubo,Wen Chieh Pi,David F. Allison,Jing Liu,Wei-Yi Chen,Lin Cai,Robert G. Roeder,Jian Jin,Gang Wang +16 more
TL;DR: Zhang et al. as mentioned in this paper reported that EZH2 has additional non-canonical functions by binding cMyc at non-PRC2 targets and uses a hidden transactivation domain (TAD) for (co)activator recruitment and gene activation.
Journal ArticleDOI
BAHCC1 binds H3K27me3 via a conserved BAH module to mediate gene silencing and oncogenesis
Huitao Fan,Jiuwei Lu,Yiran Guo,Dongxu Li,Zhi-Min Zhang,Yi-Hsuan Tsai,Wen Chieh Pi,Jeong Hyun Ahn,Weida Gong,Yu Xiang,David F. Allison,Huimin Geng,Shenghui He,Yarui Diao,Wei Yi Chen,Brian D. Strahl,Ling Cai,Jikui Song,Gang Greg Wang +18 more
TL;DR: An H3K27me3-directed transduction pathway in mammals that relies on a conserved BAH 'reader' is identified, leading to suppression of oncogenesis in mice.