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Weidong Han
Researcher at Sir Run Run Shaw Hospital
Publications - 123
Citations - 12142
Weidong Han is an academic researcher from Sir Run Run Shaw Hospital. The author has contributed to research in topics: Autophagy & Cancer. The author has an hindex of 34, co-authored 103 publications receiving 9472 citations. Previous affiliations of Weidong Han include Zhejiang University.
Papers
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Journal ArticleDOI
A microRNA disease signature associated with lymph node metastasis of lung adenocarcinoma
Shu Yi Cen,Kai You Fu,Yue Shi,Han Liang Jiang,Jia Wei Shou,Liang Kun You,Weidong Han,Hong Ming Pan,Zhen Liu +8 more
TL;DR: The miRNA disease signature can be used as a noninvasive method to predict LNM in patients with lung adenocarcinoma objectively and the signature achieved high accuracy for prediction.
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The roles of transmembrane family proteins in the regulation of store-operated Ca2+ entry
TL;DR: The TMEM proteins that are involved in SOCE are summarized to better describe a picture of the interaction between STIM and ORAI proteins during SOCE and its downstream signaling pathways, as well as to provide an idea for the study of the TMEM family proteins.
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Lymph node involvement in pancreatic neuroendocrine tumors: significance as a predictor of survival
Li Yu,Rongjie Zhao,Xufeng Han,Jiawei Shou,Liangkun You,Hanliang Jiang,Xiaoyun Zhou,Zhen Liu,Hongming Pan,Weidong Han +9 more
TL;DR: A lymph node involvement model was developed based on the predictors including age, marital status, primary site, T status, and tumor grade and showed great performance in C-index and area under receiver operating characteristic curve.
Journal ArticleDOI
Combination treatment of radiofrequency ablation and peptide neoantigen vaccination: Promising modality for future cancer immunotherapy
Jiawei Shou,Fan Mo,Shanshan Zhang,Lantian Lu,N. Han,Liang Liu,Min Qiu,Hongsen Li,Weidong Han,Dong-sheng Ma,Xiaojie Guo,Qianpeng Guo,Q. Huang,Xiaomeng Zhang,Shengli Ye,Hongming Pan,Shuqing Chen +16 more
TL;DR: In this paper , the authors investigated the synergistic effects of radiofrequency ablation (RFA) and neoantigen vaccination in cancer patients and tumor-bearing mice and found that the combination of PD-1 blockage with RFA and neo-antigen vaccines further enhanced the antitumor response in mice.
Patent
Chimeric antigen receptor, gene of chimeric antigen receptor, recombinant expression vector of chimeric antigen receptor, CD22-CD19 double-targeting T cell and application of cell
TL;DR: In this paper, the chimeric antigen receptor was used to detect tumor cells co-expressed by two target spots of the CD19 antigen and the CD22antigen, compared with the single target spot CAR T, the double target spots CAR T have stronger anti-tumor activity, so that the immune escape of the tumor cells expressed by the low-abundance antigen is avoided, and therefore the recurrence risk is reduced.