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Weidong Han
Researcher at Sir Run Run Shaw Hospital
Publications - 123
Citations - 12142
Weidong Han is an academic researcher from Sir Run Run Shaw Hospital. The author has contributed to research in topics: Autophagy & Cancer. The author has an hindex of 34, co-authored 103 publications receiving 9472 citations. Previous affiliations of Weidong Han include Zhejiang University.
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Nanodelivery of a self-assembling prodrug with exceptionally high drug loading potentiates chemotherapy efficacy
TL;DR: In this article, a self-assembling dimeric cabazitaxel prodrug is quantitatively entrapped within clinically approved polymer matrices for intravenous injection and the drug loading in the nanoparticles (NPs) is tunable.
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Identification of a STIM1 Splicing Variant that Promotes Glioblastoma Growth
Jiansheng Xie,Guolin Ma,Lijuan Zhou,Lin He,Zhao Zhang,Peng Tan,Zixian Huang,Shaohai Fang,Tianlu Wang,Yi-Tsang Lee,Shufan Wen,Stefan Siwko,Liuqing Wang,Jindou Liu,Yangchun Du,Ningxia Zhang,Xiaoxuan Liu,Leng Han,Yu Huang,Rui Wang,Youjun Wang,Yubin Zhou,Weidong Han +22 more
TL;DR: A splicing variant‐specific tumor‐promoting role of STIM1β that can be potentially targeted for glioblastoma intervention is established.
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Quantitation of cell-free DNA in blood is a potential screening and diagnostic maker of breast cancer: a meta-analysis.
Huadi Wang,Zhen Liu,Jiansheng Xie,Zhanggui Wang,Xiaoyun Zhou,Yong Fang,Hongming Pan,Weidong Han +7 more
TL;DR: Quantification of cfDNA is a promising test in screening and diagnostic of breast cancer, but population-based standardization of test methods require completion prior to clinical use.
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Intestinal epithelial cell autophagy deficiency suppresses inflammation-associated colon tumorigenesis
TL;DR: In this paper , the role of autophagy in the initiation and progression of colon cancer was investigated in a mouse model for CAC in humans, and it was found that autophagous protection against DSS-induced intestinal injury through maintaining epithelial barrier function and promoting the survival and proliferation of IECs.
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Risk-Adapted Postmastectomy Radiotherapy Decision Based on Prognostic Nomogram for pT1-2N1M0 Breast Cancer: A Multicenter Study.
Ming Li,Jinbo Yue,Xiang-Bo Wan,Bin Hua,Qiuan Yang,Pei Yang,Zijian Zhang,Qian Pei,Weidong Han,Yaping Xu,Xuefeng Xia +10 more
TL;DR: The proposed nomogram provides an individualized risk estimate of LRFS in patients with pT1-2N1M0 breast cancer and indicates that risk-adapted PMRT for high-risk patients is a viable effective strategy.