Weiwei Gao

TL;DR: Compared to mice vaccinated with control samples, those vaccinated with the nanoparticle toxoid show superior protective immunity against MRSA skin infection and this biomimetic nanoparticle‐based toxin detainment strategy is a promising method for the design of potent antivirulence vaccines for managing bacterial infections.

TL;DR: The rapid emergence of antibiotic resistance is recognized as a major public health threat and nanomaterials have risen to tackle this problem through either improving the potency of existing antibiotics or generating entirely new antibacterial mechanisms.

TL;DR: The aim was to fabricate cellmimicking nanoparticles through a top-down approach that bypassed the labor-intensive processes of protein identification, purification, and conjugation and resulted in red-blood-cell-membrane–coated nanoparticles (RBC-NPs), which have resulted in novel delivery systems with improved drug tolerability, circulation lifetime, and efficacy.

TL;DR: The facile synthesis of ultra-small, sub-25 nm lipid-polymer hybrid nanoparticles using an adapted nanoprecipitation approach is demonstrated and their utility for targeted delivery of a model chemotherapeutic is explored.

TL;DR: The first scanning tunneling microscope investigation is reported, combined with density functional theory calculations, to resolve controversy regarding the bonding and structure of chlorine adsorbed on Au(111).