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Wen Chi Hou

Researcher at Taipei Medical University

Publications -  161
Citations -  6542

Wen Chi Hou is an academic researcher from Taipei Medical University. The author has contributed to research in topics: DPPH & Antioxidant. The author has an hindex of 43, co-authored 157 publications receiving 5994 citations. Previous affiliations of Wen Chi Hou include National Taiwan University & Academia Sinica.

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Inhibition of nitric oxide synthase inhibitors and lipopolysaccharide induced inducible NOS and cyclooxygenase-2 gene expressions by rutin, quercetin, and quercetin pentaacetate in RAW 264.7 macrophages

TL;DR: Results indicated that combinatorial treatment of L‐arginine analogs and flavonoid derivates, such as quercetin pentaacetate, effectively inhibited LPS‐induced NO and PGE2 productions, at the same time, inhibited enhanced expressions of iNOS and COX‐2 genes.
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Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca2+-dependent endonuclease

TL;DR: Experiments indicate that a decrease in intracellular peroxide level was involved in wogonin- and fisetin-induced apoptosis; activation of caspase 3 and endonuclease, induction of bax protein and suppression of Mcl-1 protein were detected in the process.
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Quercetin inhibition of tumor invasion via suppressing PKCδ/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells

TL;DR: It is suggested that OH groups at both C3' and C4' play central roles in QUE's inhibition of TPA-induced MMP-9 activation and migration, and an additional OH at C3, C5 or C7 may increase the inhibitory potency of the 3',4'-diOH flavone against TPA's activity and migration.
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Kinetics of the inhibition of renin and angiotensin I-converting enzyme by flaxseed protein hydrolysate fractions

TL;DR: The results show that the protein components of flaxseed meal possess peptide amino acid sequences that can be exploited as potential food sources of anti-hypertensive agents.
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Antioxidant Activities of Dioscorin, the Storage Protein of Yam (Dioscorea batatas Decne) Tuber

TL;DR: It is suggested that 32 kDa dioscorin, the storage protein of yam tuber, may play a role as antioxidant in tubers and may be beneficial for health when people take it as a food additive or consume yam tubers.