W
Wen-cong Liu
Publications - 28
Citations - 362
Wen-cong Liu is an academic researcher. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 5, co-authored 9 publications receiving 146 citations.
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Journal ArticleDOI
Ginsenoside Rb3 provides protective effects against cisplatin-induced nephrotoxicity via regulation of AMPK-/mTOR-mediated autophagy and inhibition of apoptosis in vitro and in vivo.
Jing-jing Xing,Jin-Gang Hou,Zhi-na Ma,Zi Wang,Shen Ren,Ying-Ping Wang,Wen-cong Liu,Chen Chen,Wei Li +8 more
TL;DR: This work aims to evaluate the protective effects of ginsenoside Rb3 (G‐Rb3) on cisplatin‐induced renal damage and underlying mechanisms in vivo and in vitro.
Journal ArticleDOI
Caspase-Mediated Anti-Apoptotic Effect of Ginsenoside Rg5, a Main Rare Ginsenoside, on Acetaminophen-Induced Hepatotoxicity in Mice.
TL;DR: It is demonstrated that G-Rg5 exerts a liver protection effect against APAP-induced acute hepatotoxicity mainly via a caspase-mediated anti-apoptotic effect.
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Arginyl-fructosyl-glucose, a Major Maillard Reaction Product of Red Ginseng, Attenuates Cisplatin-Induced Acute Kidney Injury by Regulating Nuclear Factor κB and Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathways
Rong-Yan Li,Wei-Zhe Zhang,Xiao-Tong Yan,Jin-Gang Hou,Zi Wang,Ding Chuanbo,Wen-cong Liu,Yinan Zheng,Chen Chen,Yue-Ru Li,Wei Li +10 more
TL;DR: AFG relieved CDDP-induced inflammation and apoptosis in part by mitigating the cascade initiation steps of nuclear factor κB signals and regulating the participation of the phosphatidylinositol 3-kinase/protein kinase B signal pathway.
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Alleviative effects of 20(R)-Rg3 on HFD/STZ-induced diabetic nephropathy via MAPK/NF-κB signaling pathways in C57BL/6 mice
Ying Li,Jin-Gang Hou,Zhi Liu,Xiao-jie Gong,Jun-nan Hu,Ying-Ping Wang,Wen-cong Liu,Xiang-Hui Lin,Zi Wang,Wei Li +9 more
TL;DR: In this paper, the authors explored the alleviative effects of 20(R)-ginsenoside Rg3 on type 2 diabetes (T2D) patients in mice and found that 20 (R)-Rg3 not only attenuated FBG levels and advanced glycation end products (AGEs) levels but also improved insulin (INS) level, blood lipids, oxidative stress, and renal function by regulating MAPKs and NF-κB signal pathways.
Journal ArticleDOI
Dietary α-Mangostin Provides Protective Effects against Acetaminophen-Induced Hepatotoxicity in Mice via Akt/mTOR-Mediated Inhibition of Autophagy and Apoptosis
TL;DR: The findings proved novel perspectives that detoxification effect of α-MG on acetaminophen-induced ALI might be due to the alterations in Akt/mTOR pathway in the liver.