Showing papers in "Journal of Ethnopharmacology in 2021"

TL;DR: The therapeutical potential of new plants included in the modern edition of the Russian Pharmacopoeia, implemented in 2018, are highlighted, underlining their therapeutic potential and significance for global phytopharmacotherapy.

TL;DR: The inhibitory effect of TCM and natural medicine on tumors was reflected in multiple levels and multiple pathways, providing reasonable evidence for new drug development.

TL;DR: Wang et al. as mentioned in this paper reviewed the use of Chinese herbal medicine in the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection both in vitro and in clinical practice.

TL;DR: Taken together, MEAH can be recommended as a potent source of neuroprotective and a libido-boosting drug candidate for the management of neurological and sexual disorders.

TL;DR: In this paper, the authors measured anti SARS-CoV-2 activity against fully infectious virus of dried leaf extracts of seven cultivars of A. annua sourced from four continents.

TL;DR: In this article, the authors provide a brief overview of the potential pharmacological mechanisms of THMs (active constituents, extracts, and prescriptions) in RA treatment, including anti-RA effects and therapeutic targets of distinct dosage forms of traditional herbal medicines (THMs).

TL;DR: The species included in the genus Scutellaria can be used to treat cancer, infection, hepatic disorders, cardiovascular and cerebrovascular diseases, neurodegenerative diseases, and other diseases.

TL;DR: Various pharmacological activities have been demonstrated, especially improving gastrointestinal function and thus allowed to assert most of the traditional uses of AR, and its long-term toxicity in vivo and clinical efficacy is explored.

TL;DR: A large number of phytochemical and pharmacological reports have indicated that Paeonia is an important medicinal herb resource, and some of its traditional uses including the treatment of inflammation and cardiovascular diseases and its use as a neuroprotective agent have been partially confirmed through modern pharmacological studies.

TL;DR: In this paper, the anti-nociceptive and anti-inflammatory properties of Ophiorrhiza rugosa var. prostrata were scrutinized using chemical and heat-induced pain models.

TL;DR: The present study suggested that QHF is curative in DSS-induced colitis by restoring gut microbiota-metabolism homeostasis and goblet cells function, shedding light on potential new drug combination for the treatment of IBD.

TL;DR: The promising preliminary data of other Gynostemma species indicated the research potential of this genus, both in phytochemical and pharmacological aspects, and clinical data are required to evaluate the efficacy and undesired effects of crude extracts, standard saponin fractions, and pure compounds prepared from Gynstemma medicinal plants.

TL;DR: A systematic review of traditional uses, chemical composition, pharmacological effect and clinical application of T. hemsleyanum aims to provide an insightful understanding of this rare herbal plant, which has become a focus of scientific attention in recent years.

TL;DR: Pharmacological evaluation confirmed the ethnomedically claimed biological actions and other beneficial effects on the skin of H. rhamnoides using scientifically accepted protocols and controls, although some of the studies require more elaborative studies.

TL;DR: Licorice flavonoids are a group of versatile molecules that have pleiotropic effects on cell growth, survival and cell signaling and have a great therapeutic potential in cancer treatment.

TL;DR: The genus Gynura (Compositae) includes around 46 species and is native to the tropical regions of Southeast Asia, Africa and Australia as mentioned in this paper, and many species within this genus are used in ethnomedicine to treat various disorders including skin diseases, injuries, ulcers, wounds, burns, sores, scalds, as well as for the management of diabetes, hypertension, hyperlipidemia, constipation, rheumatism, bronchitis and inflammation.

TL;DR: A comprehensive, accurate and authentic information on traditional uses, phytochemistry and pharmacological properties of various extracts/fractions as well as phytocostituents of A paniculata is provided in this paper.

TL;DR: The results suggest that the pharmacological properties of O. majorana confirm its traditional uses and further investigations regarding the evaluation of molecular mechanisms of identified compounds against human cancer cell lines, inflammatory process, and microbial infections are needed to validate pharmacodynamic targets.

TL;DR: Morroniside was protective against cartilage matrix degradation and reduced DMM-induced chondrocyte pyroptosis and apoptosis by the inhibition of NF-κB signaling and attenuated the progression of OA in mice.

TL;DR: In this article, the effects and mechanism of action of PS alone, and especially those of its main active component PS polysaccharide (PSP), on depression remain unexplored.

TL;DR: DXR IV exhibits potential anti-atherosclerosis effect, which is closely related to lipid metabolism and the gut microbiota, and may provide novel insights into the mechanism of DXR IV on atherosclerosis and a basis for promising clinical usage.

TL;DR: BTW significantly improved the inflammatory symptoms of mice with acute colitis, and the latent mechanism of BTW may be related to various signaling pathways, including the modulation of intestinal microflora and inflammatory pathways, such as IL-6/STAT3.

TL;DR: Zhang et al. as discussed by the authors summarized traditional uses, chemical constituents, pharmacological activities, and toxicological effects of Dendrobium leaves and found that the leaves of these plants are largely discarded.

TL;DR: This work provided an integrated strategy for revealing the combination mechanisms of Chaihu-Baishao herb pair for treating depression, and also a rational way for clarifying the composition rules of TCM.

TL;DR: Wang et al. as discussed by the authors focused on connecting the traditional "clearing heat and resolving toxicity" effect to compelling recent research advances on the antiviral effects of A. paniculata, explaining its major antiviral mechanisms, and assessing the shortcomings of existing work.

TL;DR: The research revealed the efficacy after co-administration of total polysaccharides from A. membranaceus and C. pilosula on colitis which provided a theoretical basis for their compatibility in TCM prescriptions to treat UC.

TL;DR: It is concluded that isolated andrographolide from the A. paniculata possess anti-dengue activity against dengue-2 virus as revealed from in vitro and in silico method.

TL;DR: SF might promote cholesterol transformation into bile acids and cholesterol efflux, inhibit cholesterol de novo synthesis and accelerate fatty acids oxidation for ameliorating HLP.

TL;DR: This review aimed at summarizing the latest and comprehensive information of matrine on the pharmacology, pharmacokinetics, toxicity, clinical application and preparation researches to explore the therapeutic potential of this natural ingredient.

TL;DR: This review article documented and critically assessed W. somnifera regarding its ethnopharmacology, traditional use, botanical description, phytochemicals present, pharmacological activities, clinical trials, and marketed formulations, finding it to be non-toxic and effective clinically for human health and wellness.