Wen-Juan Fu

TL;DR: A crucial role of autophagy is demonstrated in the formation of VM by GSCs, which may serve as a therapeutic target in drug-resistant glioma.

TL;DR: In this article, the authors found that the presence of CAFs containing high levels of microtubule-associated protein 1 light chain 3 (LC3II), a marker of autophagosomes, was associated with more aggressive luminal human breast cancer.

TL;DR: Investigation of expression of MPC1 and MPC2 in specimens from RCC patients and results identify anti-tumor function ofMPC1 in RCC and reveal MPC 1 as a novel prognostic biomarker to predict better patient survival.

TL;DR: Co-exposed to microcystin-LR significantly repressed the AFB1 induced malignant transformation of human hepatic cells and the glutathione S-transferase Pi positive foci formation in rat livers, suggesting that when co-exposure with AFB1, MC-LR might repress hepatocarcinogenicity of AFB1.

TL;DR: It is identified that ADP‐ribosylation factor like‐4C (ARL4C) was highly expressed in PTEN‐deficient human GBM cells and tissues and acts as a novel prognostic biomarker and a potential therapeutic candidate.