Wen L. Shih

TL;DR: Deletion analysis of the ARV ρC protein suggests that the carboxyl-terminus of σC is important in mediating σ C-induced apoptosis because its deletion abolished the induction of apoptosis.

TL;DR: The first evidence of upregulation of p53 and Bax and specifically for Bax translocation from cytosol to mitochondria following infection with a cytoplasmically replicating RNA virus is provided, suggesting that p 53 and the mitochondria-mediated pathway played an important regulatory role in ARV-induced apoptosis in BHK-21 cells.

TL;DR: A phylogenetic tree based on the nucleotide sequences of the HVR of S1 gene revealed that Taiwanese IBV isolates had evolved into three groups (TWI, TWII, and Mass), which suggested that there were multiple groups of viruses cocirculating in Taiwan.

TL;DR: The results suggested that polymerase chain reaction followed by restriction enzyme analysis provided a simple and rapid approach for characterization of ARV isolates, and whether a new variant strain has been introduced into a flock or a given virus strain has spread from one flock to another was determined.

TL;DR: This monoclonal antibody may be useful for the development of an antigen-capture enzyme-linked immunosorbent assay for rapid detection of field isolates of ARVs tested.