W
Wendy J. Levin
Researcher at University of California, Los Angeles
Publications - 4
Citations - 18677
Wendy J. Levin is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Gene & Cancer. The author has an hindex of 4, co-authored 4 publications receiving 17959 citations.
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Journal ArticleDOI
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene
Dennis J. Slamon,Gary M. Clark,Steven G. Wong,Wendy J. Levin,Axel Ullrich,William L. McGuire +5 more
TL;DR: Amplification of the HER-2/neu gene was a significant predictor of both overall survival and time to relapse in patients with breast cancer, and had greater prognostic value than most currently used prognostic factors in lymph node-positive disease.
Journal ArticleDOI
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer.
Dennis J. Slamon,William Godolphin,Lovell A. Jones,John A. Holt,Steven G. Wong,Duane E. Keith,Wendy J. Levin,Susan G. Stuart,Judy Udove,Axel Ullrich,Michael F. Press +10 more
TL;DR: The concept that the HER-2/neu gene may be involved in the pathogenesis of some human cancers, including breast and ovarian cancer, is supported.
Journal Article
Expression patterns of immediate early transcription factors in human non-small cell lung cancer. The Lung Cancer Study Group.
Wendy J. Levin,Michael F. Press,R B Gaynor,Vikas P. Sukhatme,T C Boone,P T Reissmann,Robert A. Figlin,E C Holmes,L M Souza,Dennis J. Slamon +9 more
TL;DR: Northern blot analyses revealed that 72% of the normal tissues demonstrate significantly greater expression of these transcription factors as compared to adjacent malignant tissue, and data suggest that down-regulation of these genes may be involved in the pathogenesis of lung cancer.
Journal ArticleDOI
Tumor Suppressor and Immediate Early Transcription Factor Genes in Non-small Cell Lung Cancer
Wendy J. Levin,Graham Casey,Juan Carlos Ramos,M. Jane Arboleda,P T Reissmann,Dennis J. Slamon +5 more
TL;DR: Northern blot and immunohistochemical analysis showed that these tumors exhibited changes in the mRNA and protein expression levels respectively of the immediate early transcription factor genes c-fos, c-jun, and EGR, in that less expression of these genes was evident in the tumors compared with adjacent normal tissue.