Wenjun Zhu

TL;DR: This work develops a facile approach to fabricate PEGylated 1D‐NCPs with tumor‐specific pH responsiveness and theranostic functionalities, and presents a unique low‐temperature PTT strategy to kill cancer in a highly effective and minimally invasive manner.

TL;DR: This work develops a simple yet general method with which to fabricate DNA-based NCPs and presents an interesting concept of a nanoscale drug-delivery system that could achieve the intranuclear delivery of photosensitizers, the down-regulation of anti-apoptotic proteins, and the modulation of the unfavorable tumor microenvironment simultaneously for improved cancer therapy.

TL;DR: This work highlights the promise of ultra-small iron coordination nanoparticles for imaging-guided cancer therapy and utilizes Fe-GA-PEG CPNs for in vivo photothermal therapy and achieve highly effective tumor destruction after i.v. injection.

TL;DR: 2D-NMOFs composed of Zn2+ and tetrakis(4-carboxyphenyl) porphyrin (TCPP) are fabricated and functionalized with polyethylene glycol (PEG) and show great promise for nanomedicine applications.

TL;DR: Chemotherapy with Ca/Pt(IV)@pHis-PEG NCPs in the animal tumor model demonstrates great efficacy under low drug doses, and is found to be particularly effective towards solid tumors with reduced pH.