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Wenlin Huang
Researcher at Sun Yat-sen University
Publications - 139
Citations - 6995
Wenlin Huang is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Nasopharyngeal carcinoma & Cell growth. The author has an hindex of 41, co-authored 136 publications receiving 6205 citations. Previous affiliations of Wenlin Huang include Princeton University & Chinese Academy of Sciences.
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Journal ArticleDOI
Cellular microRNAs contribute to HIV-1 latency in resting primary CD4 + T lymphocytes
Jialing Huang,Feng-xiang Wang,Elias G. Argyris,Keyang Chen,Zhihui Liang,Zhihui Liang,Heng Tian,Wenlin Huang,Kathleen Squires,Gwen Verlinghieri,Hui Zhang +10 more
TL;DR: It is shown that cellular microRNAs (miRNAs) potently inhibit HIV-1 production in resting primary CD4+ T cells and that manipulation of cellular miRNAs could be a novel approach for purging the HIV- 1 reservoir.
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The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells
Li Bing Song,Jun Li,Wen Ting Liao,Yan Feng,Chunping Yu,Li Juan Hu,Qing Li Kong,Lihua Xu,Xing Zhang,Wan Li Liu,Man Zhi Li,Ling Zhang,Tie Bang Kang,Li Wu Fu,Wenlin Huang,Yun Fei Xia,Sai Wah Tsao,Mengfeng Li,Vimla Band,Hamid Band,Qinghua Shi,Yi Xin Zeng,Mu Sheng Zeng +22 more
TL;DR: It is found that upregulation of Bmi-1 induced epithelial-mesenchymal transition (EMT) and enhanced the motility and invasiveness of human nasopharyngeal epithelial cells, whereas silencing endogenous Bmi -1 expression reversed EMT and reduced motility.
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Bmi-1 Is a Novel Molecular Marker of Nasopharyngeal Carcinoma Progression and Immortalizes Primary Human Nasopharyngeal Epithelial Cells
Li Bing Song,Mu Sheng Zeng,Wen Ting Liao,Ling Zhang,Hao Yuan Mo,Wan Li Liu,Jian Yong Shao,Qiu Liang Wu,Man Zhi Li,Yun Fei Xia,Li Wu Fu,Wenlin Huang,Goberdhan P. Dimri,Vimla Band,Yi Xin Zeng +14 more
TL;DR: This study provides the first cellular proto-oncogene immortalized nasopharyngeal epithelial cell line, which may serve as a cell model system for studying the mechanisms involved in the tumorigenesis of nasopharygeal carcinoma.
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Cellular MicroRNAs Inhibit Replication of the H1N1 Influenza A Virus in Infected Cells
TL;DR: The findings support the notion that any miRNA has antiviral potential, independent of its cellular function, and that the cellular miRNAs play an important role in the host, defending against virus infection.
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miR-125b Is Methylated and Functions as a Tumor Suppressor by Regulating the ETS1 Proto-oncogene in Human Invasive Breast Cancer
Yan Zhang,Li Xu Yan,Qi Nian Wu,Ziming Du,Ziming Du,Jing Chen,Ding Zhun Liao,Ma Yan Huang,Jing Hui Hou,Qiu Liang Wu,Mu Sheng Zeng,Wenlin Huang,Yi Xin Zeng,Jian Yong Shao +13 more
TL;DR: It is reported that miR-125b is downregulated in invasive breast cancers where it predicts poor patient survival and is suggested as a potential theranostic tool in this disease.