William A. Kammerer

TL;DR: In patients with treatment-resistant bipolar depression, robust and rapid antidepressant effects resulted from a single intravenous dose of an N-methyl-D-aspartate-receptor antagonist.

TL;DR: Determination of the pathophysiological mechanisms underlying the progression of syringomyelia associated with the Chiari I malformation should improve strategies to halt progression of myelopathy.

TL;DR: The goal of this study was to measure changes in vascular permeability after HBBBD in patients with malignant brain tumors and to indicate that the increased exposure and exposure time that occur with methotrexate, the permeability of which is among the lowest of the agents currently used clinically, are limited and the disproportionate increase in brain exposure, compared to tumor exposure, may alter the therapeutic index of many drugs.

TL;DR: These findings indicate that a common mechanism, rather than different, separate mechanisms, underlies syrinx formation in these two entities, and are consistent with the theory that a spinal subarachnoid block increases spinal subARACHnoid pulse pressure above the block, producing a pressure differential across the obstructed segment of the SAS, which results in syrinX formation and progression.

TL;DR: The distribution observed via infrared mapping is consistent with distributed and complex functional representation of the cerebral cortex, rather than the traditional concept of discrete functional loci demonstrated by brief cortical stimulation during surgery and by noninvasive functional imaging techniques.