W
William Carley
Researcher at Yale University
Publications - 8
Citations - 188
William Carley is an academic researcher from Yale University. The author has contributed to research in topics: Endothelial stem cell & Endothelium. The author has an hindex of 6, co-authored 8 publications receiving 188 citations. Previous affiliations of William Carley include Miles Laboratories.
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Book ChapterDOI
Scatter factor stimulates migration of vascular endothelium and capillary-like tube formation
Eliot M. Rosen,Derek Grant,Hynta Kleinman,Susan Jaken,Maribeth A. Donovan,Eva Setter,Peter M. Luckett,William Carley,Madhu Bhargava,Itzhak D. Goldberg +9 more
TL;DR: This chapter describes the regulation by SF of vascular endothelial cell chemotaxis and chemokinesis; migration from microcarrier beads to flat surfaces; invasion through porous filters coated with reconstituted basement membrane; secretion of plasminogen activator; and in vitro capillary-like tube formation on a basement membrane surface.
Journal ArticleDOI
Regulation of motility in bovine brain endothelial cells.
Eliot M. Rosen,Susan Jaken,William Carley,Peter M. Luckett,Eva Setter,Madhu Bhargava,Itzhak D. Goldberg +6 more
TL;DR: Two pathways for BBEC motility are suggested: a PKC‐dependent pathway and an SF‐stimulated/PKC‐independent pathway.
Book ChapterDOI
Microvascular Endothelial Cells: Isolation, Identification, and Cultivation
TL;DR: This chapter discusses isolation, identification, and cultivation of microvascular endothelial cells, which has provided an important tool as to the role of the vascular endothelium of cardiac muscle in a number of physiologic and pathophysiologic functions, including prostaglandin synthesis.
Journal ArticleDOI
Scatter factor regulates vascular endothelial cell motility.
TL;DR: Preliminary studies suggest endothelial lines with cobblestone (epithelioid) morphology respond to SF, while those lines with elongated cells do not respond, and mesenchymal cell-derived cytokines may play roles in development and tissue repair.
Journal ArticleDOI
Isolation of rabbit pulmonary microvascular endothelial cells and characterization of their angiotensin converting enzyme activity
TL;DR: An in vitro model using cultured rabbit pulmonary endothelial cells of microvascular origin was developed and can be used to compare ACE and other protease kinetics in microvessel cells with those of large vessel endothelium or perfused lungs.