W
William Cenens
Researcher at University of São Paulo
Publications - 22
Citations - 993
William Cenens is an academic researcher from University of São Paulo. The author has contributed to research in topics: Xanthomonas citri & Gene. The author has an hindex of 14, co-authored 20 publications receiving 770 citations. Previous affiliations of William Cenens include Katholieke Universiteit Leuven.
Papers
More filters
Journal ArticleDOI
Engineered Endolysin-Based “Artilysins” To Combat Multidrug-Resistant Gram-Negative Pathogens
Yves Briers,Maarten Walmagh,Victor Van Puyenbroeck,Anneleen Cornelissen,William Cenens,Abram Aertsen,Hugo Alexandre Mendes Oliveira,Joana Azeredo,Gunther Verween,Jean-Paul Pirnay,Stefan Miller,Guido Volckaert,Rob Lavigne +12 more
TL;DR: This work modified endolysins by protein engineering to create Artilysins that are able to pass the outer membrane and become active against Pseudomonas aeruginosa and Acinetobacter baumannii, two of the most hazardous drug-resistant Gram-negative pathogens.
Journal ArticleDOI
Art-175 is a highly efficient antibacterial against multidrug-resistant strains and persisters of Pseudomonas aeruginosa
Yves Briers,Maarten Walmagh,Barbara Grymonprez,Manfred Biebl,Jean-Paul Pirnay,Valerie Defraine,Jan Michiels,William Cenens,Abram Aertsen,Stefan Miller,Rob Lavigne +10 more
TL;DR: Art-175 is a novel antibacterial that is well suited for a broad range of applications in hygiene and veterinary and human medicine, with a unique potential to target persister-driven chronic infections.
Journal ArticleDOI
Bacteria-Killing Type IV Secretion Systems.
Germán G. Sgro,Gabriel Umaji Oka,Diorge P. Souza,William Cenens,Ethel Bayer-Santos,Bruno Y. Matsuyama,Natalia F. Bueno,Thiago Rodrigo dos Santos,Cristina E. Alvarez-Martinez,Roberto Kopke Salinas,Chuck S. Farah +10 more
TL;DR: This review will focus on this special subtype of T4SS by describing its distinguishing features, similar systems in other proteobacterial genomes, and the nature of the effectors secreted by these systems and their cognate inhibitors.
Journal ArticleDOI
Expression of a Novel P22 ORFan Gene Reveals the Phage Carrier State in Salmonella Typhimurium
William Cenens,Mehari Tesfazgi Mebrhatu,Angella Makumi,Pieter-Jan Ceyssens,Rob Lavigne,Rob Van Houdt,François Taddei,Abram Aertsen +7 more
TL;DR: This study is the first to reveal molecular and genetic markers authenticating pseudolysogenic development, thereby exposing a novel mechanism, timing, and populational distribution in the realm of phage–host interactions.
Journal ArticleDOI
A Multifaceted Study of Pseudomonas aeruginosa Shutdown by Virulent Podovirus LUZ19
Rob Lavigne,Elke Lecoutere,Jeroen Wagemans,William Cenens,Abram Aertsen,Liliane Schoofs,Bart Landuyt,Jan Paeshuyse,Maurice Scheer,Max Schobert,Pieter-Jan Ceyssens +10 more
TL;DR: A multifaceted study combining quantitative PCR, microarray, RNA-seq, and two-dimensional gel electrophoresis to obtain a global overview of alterations in DNA, RNA, and protein content in Pseudomonas aeruginosa PAO1 cells upon infection with the strictly lytic phage LUZ19 finds new features of phage infection.