J
Jan Michiels
Researcher at Katholieke Universiteit Leuven
Publications - 207
Citations - 10808
Jan Michiels is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Rhizobium etli & Multidrug tolerance. The author has an hindex of 51, co-authored 193 publications receiving 8921 citations. Previous affiliations of Jan Michiels include Flanders Institute for Biotechnology & National Autonomous University of Mexico.
Papers
More filters
Journal ArticleDOI
Definitions and guidelines for research on antibiotic persistence
Naomi N.Q. Balaban,Sophie Helaine,Kim Lewis,Martin Ackermann,Martin Ackermann,Bree B. Aldridge,Dan I. Andersson,Mark P. Brynildsen,Dirk Bumann,Andrew Camilli,James J. Collins,James J. Collins,James J. Collins,Christoph Dehio,Sarah M. Fortune,Jean-Marc Ghigo,Wolf-Dietrich Hardt,Alexander Harms,Matthias Heinemann,Deborah T. Hung,Urs Jenal,Bruce R. Levin,Jan Michiels,Gisela Storz,Man-Wah Tan,Tanel Tenson,Laurence Van Melderen,Annelies S. Zinkernagel +27 more
TL;DR: Scientists working on the response of bacteria to antibiotics define antibiotic persistence and provide practical guidance on how to study bacterial persister cells, and provide a guide to measuring persistence.
Journal ArticleDOI
Quorum sensing and swarming migration in bacteria
TL;DR: The regulation of AHL-mediated surface migration and the involvement of other low-molecular-mass signal molecules (such as the furanosyl borate diester AI-2) in biosurfactant production of different bacteria is discussed.
Journal ArticleDOI
Living on a surface: swarming and biofilm formation
Natalie Verstraeten,Kristien Braeken,Bachaspatimayum Debkumari,Maarten Fauvart,Jan Fransaer,Jan Vermant,Jan Michiels +6 more
TL;DR: A review of recent advances in the study of the regulatory pathways that lead to swarming behavior of different model bacteria and the understanding of the transition between motile and sessile lifestyles of bacteria is provided.
Journal ArticleDOI
Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapies.
TL;DR: Current understanding of the role that persisters play in the treatment and outcome of chronic infections is reviewed and a perspective on the development of anti-persister therapies based on genes and mechanisms that have been implicated in persistence over the last decade is offered.
Journal ArticleDOI
Formation, physiology, ecology, evolution and clinical importance of bacterial persisters.
TL;DR: This work defines persistence, summarizes the various aspects of persister physiology and shows their heterogeneous nature, and focuses on the role of key cellular processes and mechanisms controlling the formation of a subpopulation of tolerant cells.